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浏览/检索结果: 共68条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer 期刊论文 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 110, 页码: 51-61 作者:  Li, Xin;  Yang, Changyong;  Wan, Hong;  Zhang, Ge;  Feng, Jun 收藏  |  浏览/下载：136/0  |  提交时间：2019/01/08 Pyrotinib  HER2-postive breast cancer  Irreversible EGFR/HER2 dual tyrosine kinase  inhibitor  Preclinical  Clinical  Safety  Drug metabolism   Theranostic Prodrug Vesicles for Reactive Oxygen Species-Triggered Ultrafast Drug Release and Local-Regional Therapy of Metastatic Triple-Negative Breast Cancer 期刊论文 ADVANCED FUNCTIONAL MATERIALS, 2017, 卷号: 27, 期号: 46 作者:  Zhou, Fangyuan;  Feng, Bing;  Wang, Tingting;  Wang, Dangge;  Cui, Zhirui 收藏  |  浏览/下载：63/0  |  提交时间：2019/01/08 cancer theranostics  local-regional therapy  prodrug vesicles  reactive oxygen species  triple-negative breast cancer   Pharmacologic characterization of SHR8443, a novel dual inhibitor of phosphatidylinositol 3-kinase and mammalian target of rapamycin 期刊论文 ONCOTARGET, 2017, 卷号: 8, 期号: 64, 页码: 107977-107990 作者:  Xie, Chengying;  Chen, Xiangling;  Zheng, Mingyue;  Liu, Xiaohong;  Wang, Hongbin 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 BEZ235  drug resistance  mTOR  PI3K  SHR8443   Co-delivery of docetaxel and silibinin using pH-sensitive micelles improves therapy of metastatic breast cancer 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1655-1662 作者:  Dong, Xin-yue;  Lang, Tian-qun;  Yin, Qi;  Zhang, Peng-cheng;  Li, Ya-ping 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 pH-sensitive polymer  co-delivery  micelle  docetaxel  silibinin  breast cancer  mouse breast cancer cell line 4T1  metastasis   Dual-Targeting to Cancer Cells and M2 Macrophages via Biomimetic Delivery of Mannosylated Albumin Nanoparticles for Drug-Resistant Cancer Therapy 期刊论文 ADVANCED FUNCTIONAL MATERIALS, 2017, 卷号: 27, 期号: 44 作者:  Zhao, Pengfei;  Yin, Weimin;  Wu, Aihua;  Tang, Yisi;  Wang, Jinyu 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 albumin nanoparticles  combination therapy  mannose receptors  multidrug resistance  SPARC   PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KII alpha, Inhibits the Growth of Breast Cancer Cells 期刊论文 CANCER RESEARCH, 2017, 卷号: 77, 期号: 22, 页码: 6253-6266 作者:  Li, Jiangmei;  Gao, Zhen;  Zhao, Dan;  Zhang, Lunfeng;  Qiao, Xinhua 收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Supramolecular assembly of fluorogenic glyco-dots from perylenediimide-based glycoclusters for targeted imaging of cancer cells 期刊论文 CHEMICAL COMMUNICATIONS, 2017, 卷号: 53, 期号: 87, 页码: 11937-11940 作者:  Liu, Ying;  Ji, Ding-Kun;  Dong, Lei;  Galanos, Nicolas;  Zang, Yi 收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 New Insights into PI3K Inhibitor Design using X-ray Structures of PI3K alpha Complexed with a Potent Lead Compound 期刊论文 SCIENTIFIC REPORTS, 2017, 卷号: 7 作者:  Yang, Xiuyan;  Zhang, Xi;  Huang, Min;  Song, Kun;  Li, Xuefen 收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532 作者:  Chen, Wen-hua;  Song, Shan-shan;  Qi, Ming-hui;  Huan, Xia-juan;  Wang, Ying-qing 收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 PARP-1 inhibitor  olaparib  breast cancer  BRCA-deficient tumors   The miR-491-3p/Sp3/ABCB1 axis attenuates multidrug resistance of hepatocellular carcinoma 期刊论文 CANCER LETTERS, 2017, 卷号: 408, 页码: 102-111 作者:  Zhao, Yang;  Qi, Xinming;  Chen, Jing;  Wei, Wenxin;  Yu, Cunzhi 收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 Hepatocellular carcinoma  ABCB1  Sp3  miR-491-3p  Multidrug resistance