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科研机构
上海药物研究所 [6]
植物研究所 [4]
北京大学 [3]
江苏大学 [3]
中南大学 [2]
武汉大学 [2]
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期刊论文 [30]
发表日期
2016 [30]
学科主题
Biochemist... [2]
Biophysics [2]
Plant Scie... [2]
plant scie... [1]
医学心理学 [1]
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Optimal dietary alpha-linolenic acid/linoleic acid ratio improved digestive and absorptive capacities and target of rapamycin gene expression of juvenile grass carp (Ctenopharyngodon idellus)
期刊论文
AQUACULTURE NUTRITION, 2016, 卷号: 22, 期号: 6, 页码: 1251-1266
作者:
Zeng, Y. -Y.
;
Jiang, W. -D.
;
Liu, Y.
;
Wu, P.
;
Zhao, J.
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/09/05
absorption
alpha-linolenic acid
Ctenopharyngodon idellus
digestion
linoleic acid
TOR signalling pathway
Agglutinin isolated from Arisema heterophyllum Blume induces apoptosis and autophagy in A549 cells through inhibiting PI3K/Akt pathway and inducing ER stress
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2016, 卷号: 14, 期号: 11, 页码: 856-864
作者:
Feng Li-Xing
;
Sun Peng
;
Mi Tian
;
Liu Miao
;
Liu Wang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Agglutinin
Arisaema heterophyllum Blume
Human non-small-cell lung cancer A549 cell line
Apoptosis
Autophagy
Quantitative profiling of spreading-coupled protein tyrosine phosphorylation in migratory cells
期刊论文
Scientific reports, 2016, 卷号: 6, 页码: 10
作者:
Xie, Yajun
;
Wang, Jinlong
;
Zhang, Yuanya
;
Liu, Xiaofei
;
Wang, Xiaorong
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/05/09
Development of Heat Shock Protein (Hsp90) Inhibitors To Combat Resistance to Tyrosine Kinase Inhibitors through Hsp90-Kinase Interactions
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 12, 页码: 5563-5586
作者:
Wang, Meining
;
Shen, Aijun
;
Zhang, Chi
;
Song, Zilan
;
Ai, Jing
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Plasma levels of growth differentiation factor-15 are associated with myocardial injury in patients undergoing off-pump coronary artery bypass grafting
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:
Yuan, Zhize
;
Li, Haiqing
;
Qi, Quan
;
Gong, Wenhui
;
Qian, Cheng
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II-III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
期刊论文
CHEMICAL REVIEWS, 2016, 卷号: 116, 期号: 2, 页码: 422-518
作者:
Zhou, Yu
;
Wang, Jiang
;
Gu, Zhanni
;
Wang, Shuni
;
Zhu, Wei
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Regulator of G-Protein Signaling 10 Negatively Regulates Cardiac Remodeling by Blocking Mitogen-Activated Protein Kinase-Extracellular Signal-Regulated Protein Kinase 1/2 Signaling
期刊论文
Hypertension (Dallas, Tex. : 1979), 2016, 卷号: 67, 期号: 1, 页码: 86-98
作者:
Miao, Rujia
;
Lu, Yao
;
Xing, Xiaowei
;
Li, Ying
;
Huang, Zhijun
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/03
angiotensin II
cardiomegaly
extracellular signal-regulated MAP kinases
mitogen-activated protein kinase kinases
signal transduction
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells
期刊论文
Cellular Signalling, 2016, 卷号: 28, 期号: 8, 页码: 1099-1104
作者:
Wang, Jing
;
Yang, Xin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/03
4E-BP1
4E binding protein
AMPK
AMP-activated protein kinase
ATF6
activating transcription factor 6
ATP
adenosine triphosphate
DEPTOR
DEP domain containing mTOR-interacting protein
CI
complexes I
CII
complex II
CIII
complex III
CIV
complex IV
CV
complex V
eIF2α
Eukaryotic Initiation Factor 2α
ER
Endoplasmic Reticulum
ERAD
ER-associated degradation
ERO1α
ER oxidoreductase 1 α
FoxO1
Forkhead box O1
GβL
G Protein β Subunit Like Protein
GRP78
78 kDa glucose-regulated protein precursor
GSIS
glucose-stimulated insulin secretion
IRE1
Inositol-requiring enzyme 1
IRS1
Insulin receptor substrate 1
IRS2
Insulin receptor substrate 2
mLST8
mammalian lethal with sec-13 protein 8
mSin1
the mammalian stress-activated MAP kinase-interaction protein 1
mtDNA
mitochondrial deoxyribonucleic acid
mTOR
mammalian TOR
mTORC1
mTOR complex 1
mTORC2
mTOR complex 2
NADPH oxidase
Nicotinamide adenine dinucleotide phosphate-oxidase
NOS
nitric oxide synthase
O2–·
superoxide anion
H2O2
hydrogen peroxide
OH·
hydroxyl radical
3O2
triplet-state molecular oxygen
OXPHOS
oxidative phosphorylation
CAT
catalase
GPx
glutathioneperoxidase
PERK
Protein kinase R-like endoplasmic reticulum kinase
PDI
ER protein disulfide isomerases
PI3K
the phosphoinositide3-kinase
PRAS40
40-kDa proline-rich Akt substrate
PRAS40
the 40-kDa proline-rich Akt substrate
PROTOR
the protein observed with RICTOR
RAPTOR
regulatory-associated protein of mTOR
RICTOR
The rapamycin-insensitive companion of mTOR
REDD1
DNA damage response 1
RNS
reactive nitrogen species
ROS
reactive oxygen species
RNS
reactive nitrogen species
S6K
S6 kinase
SOD
superoxidedismutase
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TOR
the target of rapamycin
TSC2
Tuberous sclerosis 2
UPR
unfolded protein response
Mitochondrial oxidative stress
ER stress
mTOR
Pancreatic β cells
The rLrp of Mycobacterium tuberculosis inhibits proinflammatory cytokine production and downregulates APC function in mouse macrophages via a TLR2-mediated PI3K/Akt pathway activation-dependent mechanism
期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2016
Liu, Yuan
;
Li, Jia-Yun
;
Chen, Su-Ting
;
Huang, Hai-Rong
;
Cai, Hong
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
APC function
cytokine
Mycobacterium tuberculosis
rLrp
TLR2 and PI3 K/Akt pathway
NF-KAPPA-B
TOLL-LIKE RECEPTORS
NITRIC-OXIDE PRODUCTION
NECROSIS-FACTOR-ALPHA
INNATE IMMUNITY
ANTIGEN PRESENTATION
MURINE MACROPHAGES
19-KDA LIPOPROTEIN
INTERFERON-GAMMA
TNF-ALPHA
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