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科研机构
上海药物研究所 [3]
武汉大学 [3]
南华大学 [2]
四川大学 [2]
华南理工大学 [2]
昆明医科大学 [2]
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内容类型
期刊论文 [22]
会议论文 [1]
其他 [1]
发表日期
2016 [24]
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发表日期:2016
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Small molecule lx2343 ameliorates cognitive deficits in ad model mice by targeting both amyloid beta production and clearance
期刊论文
Acta pharmacologica sinica, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:
Guo, Xiao-dan
;
Sun, Guang-long
;
Zhou, Ting-ting
;
Xu, Xin
;
Zhu, Zhi-yuan
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/05/09
Alzheimer's disease
N-(1,3-benzodioxol-5-yl)-2-[5-chloro-2-methoxy(phenylsulfonyl)anilino]acetamide (lx2343)
Streptozotocin
Amyloid beta
Pi3k
Autophagy
App/ps1 transgenic mice
Cognitive deficit
Bace1
Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid beta production and clearance
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:
Guo, Xiao-dan
;
Sun, Guang-long
;
Zhou, Ting-ting
;
Xu, Xin
;
Zhu, Zhi-yuan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Alzheimer's disease
N-(1,3-benzodioxol-5-yl)-2-[5-chloro-2-methoxy(phenylsulfonyl)anilino]acetamide (LX2343)
streptozotocin
amyloid beta
BACE1
PI3K
autophagy
APP/PS1 transgenic mice
cognitive deficit
Autophagic flux is highly active in early mitosis and differentially regulated throughout the cell cycle
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 26, 页码: 39705-39718
作者:
Li, Zhiyuan
;
Ji, Xinmiao
;
Wang, Dongmei
;
Liu, Juanjuan
;
Zhang, Xin
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2017/11/16
Mitosis
Autophagy
Autophagic Flux
Lc3
Cell Synchronization
Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR
期刊论文
PLOS ONE, 2016, 卷号: 11, 期号: 4, 页码: 1-24
作者:
Li, Zhiyuan
;
Ji, Xinmiao
;
Wang, Wenchao
;
Liu, Juanjuan
;
Liang, Xiaofei
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2017/11/10
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 30
作者:
Liao, Chenghui
;
Zheng, Kai
;
Li, Yan
;
Xu, Hong
;
Kang, Qiangrong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/04
ROS
unfolded protein response
autophagic flux inhibition
vacuolation
Ca2+ release
Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage checkpoint
期刊论文
AUTOPHAGY, 2016, 卷号: 12, 期号: 9
作者:
Zheng, Kai
;
Li, Yan
;
Wang, Shaoxiang
;
Wang, Xiao
;
Liao, Chenghui
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/04
autophagic flux
chemoresistance
DNA damage checkpoint
esophageal cancer
estrogen receptor
ginsenoside Ro
NADPH oxidases
ROS
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release
期刊论文
2016, 卷号: 7, 期号: [db:dc_citation_issue], 页码: 47387
作者:
Liao, Chenghui[1]
;
Zheng, Kai[1,2]
;
Li, Yan[3]
;
Xu, Hong[4]
;
Kang, Qiangrong[1]
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/03
Cationic liposomes induce cell necrosis through lysosomal dysfunction and late-stage autophagic flux inhibition
期刊论文
NANOMEDICINE, 2016, 卷号: 11
作者:
Yang, Kaixuan[1,2,3,4]
;
Lu, Ying[1]
;
Xie, Fangyuan[1,5]
;
Zou, Hao[1]
;
Fan, Xiaoyu[2]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/24
autophagic flux
cationic liposomes
cellular toxicity
gene therapy
lysosome membrane permeabilization
necrosis
Acute hyperglycemia suppresses left ventricular diastolic function and inhibits autophagic flux in mice under prohypertrophic stimulation
期刊论文
CARDIOVASCULAR DIABETOLOGY, 2016, 卷号: 15
作者:
Xie, Jiahe[1]
;
Cui, Kai[1]
;
Hao, Huixin[1]
;
Zhang, Yingxue[1]
;
Lin, Hairuo[1]
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/04/24
Acute hyperglycemia
Diastolic function
Myocardial hypertrophy
Autophagic flux
Codelivery of a miR-124 mimic and obatoclax by cholesterol-penetratin micelles simultaneously induces apoptosis and inhibits autophagic flux in breast cancer in vitro and in vivo
期刊论文
Molecular Pharmaceutics, 2016, 卷号: Vol.13 No.7, 页码: 2466-2483
作者:
Zhang, N.
;
Huang, Y.
;
Wu, F.
;
Zhao, Y.
;
Li, X.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/02/25
apoptosis
autophagic
flux
breast
cancer
miR-124
obatoclax
penetratin
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