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The apelin-APJ axis: A novel potential therapeutic target for organ fibrosis 期刊论文
Clinica Chimica Acta, 2016, 卷号: 456, 页码: 81-88
作者:  Huang, Shifang;  Chen, Linxi;  Lu, Liqun;  Li, Lanfang*
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/27
AT-1  angiotensin II type 1 receptor  VSMC  vascular smooth muscle cell  TGF-β1  transforming growth factor-β1  Ang-II  angiotensin II  ECM  extracellular matrix  CKD  chronic kidney disease  eNOS  endothelial nitric oxide synthase  UUO  unilateral ureteral obstruction  EMT  epithelial–mesenchymal transition  CAD  coronary artery disease  PAI-1  plasminogen activator inhibitor-1  SphK1  sphingosine kinase1  Post-MI  post-myocardial infarction  BMCs  bone marrow cells  HSCs  hepatic stellate cells  BA  biliary atresia  AII  angiotensin II  ET-1  endothelin-1  PDGFRβ  platelet-derived growth factor receptor β  ALC  alcoholic liver cirrhosis  HCV  hepatitis C virus  BA  biliary atresia  BPD  bronchopulmonary dysplasia  ARDS  acute respiratory distress syndrome  OA  oleic acid  PH  pulmonary hypertension  KLF2  Kruppel-like factor 2  Apelin–APJ  Renal fibrosis  Cardiac fibrosis  Liver fibrosis  Pulmonary fibrosis  
Autophagy: A double-edged sword in intervertebral disk degeneration 期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2016, 卷号: 457, 页码: 27-35
作者:  Zhang, Shu-Jun;  Yang, Wei;  Wang, Cheng;  He, Wen-Si;  Deng, Hai-Yang
收藏  |  浏览/下载:15/0  |  提交时间:2019/12/27
IVD  intervertebral disk  NP  nucleus pulposus  AF  annulus fibrosus  CEPs  cartilaginous endplates  ECM  extracellular matrix  Col II  type II collagen  Col I  type I collagen  IDD  intervertebral disk degeneration  LBP  low back pain  miRNAs  microRNAs  ADAMTS  a disintegrin and metalloprotease with thrombospondin motif  MMP  matrix metalloproteinases  HSC70  heat shock cognate protein of 70 kDa  LAMP2A  lysosome-associated membrane protein type-2 A  Atg  autophagy-related genes  ULK  uncoordinated-51-like kinase  PI3KCIII  class III phosphatidylinositol 3-kinase  mTORC1  mammalian target of rapamycin complex 1  DFCP1  double FYVE-containing protein 1  3-MA  3-methyladenine  LC3  microtubule-associated protein 1 light chain 3  PE  phosphatidyl ethanolamine  LAMP-2  lysosomal membrane protein 2  TNF-α  tumor necrosis factor-α  IL-1β  interleukin-1β  NF-κB  nuclear factor-κB  JNK  c-Jun N-terminal kinase  SIRT1  silent mating type information regulator 2 homolog 1  TGF-β1  transforming growth factor-β1  ERK1/2  extracellular signal-regulated kinase 1/2  GRP78  glucose regulated protein 78  H2O2  hydrogen peroxide  Autophagy  IVD  IDD  NP  AF  


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