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Down-regulation of G9a triggers DNA damage response and inhibits colorectal cancer cells proliferation 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 5, 页码: 2917-+
作者:  Zhang, Jie;  He, Pengxing;  Xi, Yong;  Geng, Meiyu;  Chen, Yi
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
G9a Inhibition Induces Autophagic Cell Death via AMPK/mTOR Pathway in Bladder Transitional Cell Carcinoma 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: [db:dc_citation_issue]
作者:  Li, Feng;  Zeng, Jin;  Gao, Yang;  Guan, Zhenfeng;  Ma, Zhenkun
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/02
组蛋白甲基化转移酶G9a的最新研究进展 期刊论文
生命科学仪器, 2015, 期号: 2
作者:  薛伟丽;  孙瑜;  郑凌
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/05
Epigenetic targets and drug discovery Part 2: Histone demethylation and DNA methylation 期刊论文
Pharmacology and Therapeutics, 2015, 卷号: 151, 页码: 121-140
作者:  Liu, Ke;  Liu, Yanli;  Lau, Johnathan L;  Min, Jinrong*
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/23
Histone demethylation  DNA methylation  Inhibitor  Chemical probe  Drug discovery  LSD  lysine-specific histone demethylase  HDAC  histone deacetylase  REST  REST corepressor  DNMT  DNA methyltransferase  MAO  monoamine oxidase  AML  acute myeloid leukemia  KDM  lysine-specific demethylase  MLL  mixed lineage leukemia  FAD  flavin adenine dinucleotide  PCPA  trans-2-phenylcyclopropylamine  2,4-PDCA  2, 4-pyridinedicarboxylic acid  PHD  plant homeobox domain  SCLC  small cell lung cancer  JHDMs  JmjC-domain-containing histone demethylases  NOG  N-oxalylglycine  IOX1  5-carboxy-8-hydroxyquinoline  MDS  myelodysplastic syndrome  2-OG, 2-oxoglutarate or  α-ketoglutarate  G9a  euchromatic histone-lysine N-methyltransferase 2  CoREST complex  restin corepressor complex  SAH  S-adenosyl-l-homocysteine  l  SWI complex  ATP dependent chromatin remodeling complexes  Pan-Histone Demethylase Inhibitor  the inhibitor can simultaneously inhibit both LSDs and JHDMs  LSC colony  leukemic stem cell colony  Pan JmjC domain-containing demethylase inhibitor  the inhibitor can simultaneously inhibit all the members of JHDMs  E2F1  E2F transcription factor 1  E2F2  E2F transcription factor 2  RCC  renal cell carcinoma  


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