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浏览/检索结果: 共5条，第1-5条 帮助 限定条件 发表日期：2012    专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Identifying Allosteric Binding Sites in Proteins with a Two-State G(o)over-bar Model for Novel Allosteric Effector Discovery 期刊论文 journal of chemical theory and computation, 2012 Qi, Yifei; Wang, Qian; Tang, Bo; Lai, Luhua 收藏  |  浏览/下载：2/0  |  提交时间：2015/11/12 LOCAL MOTIONS  D-3-PHOSPHOGLYCERATE DEHYDROGENASE  MOLECULAR-DYNAMICS  SUBSTRATE-BINDING  POPULATION-SHIFT  ENERGY LANDSCAPE  DRUG DISCOVERY  NETWORK MODEL  INHIBITION  KINASE   Dynamic eicosanoid responses upon different inhibitor and combination treatments on the arachidonic acid metabolic network 期刊论文 分子生物系统, 2012 He, Chong; Wu, Yiran; Lai, Yongquan; Cai, Zongwei; Liu, Ying; Lai, Luhua 收藏  |  浏览/下载：12/0  |  提交时间：2015/11/10 PROSTAGLANDIN E-2 SYNTHASE-1  MECHANISM-BASED INACTIVATION  HUMAN WHOLE-BLOOD  DEFICIENT MICE  POLYMORPHONUCLEAR LEUKOCYTES  5-LIPOXYGENASE 5-LOX  CELL-PROLIFERATION  TUMOR-ANGIOGENESIS  DUAL INHIBITORS  DRUG DESIGN   Identification of the Significant Involvement and Mechanistic Role of CYP3A4/5 in Clopidogrel Bioactivation 期刊论文 acs medicinal chemistry letters, 2012 Zhu, Yaoqiu; Zhou, Jiang 收藏  |  浏览/下载：4/0  |  提交时间：2015/11/11 Clopidogrel resistance  prodrug attrition  CYP3A4/5  active metabolite potentiation  piperidine metabolism  ANTIPLATELET TREATMENT  RESPONSE VARIABILITY  PLATELET REACTIVITY  CLINICAL-EFFICACY  CYP2C19 GENOTYPE  CYTOCHROMES P450  HIGHLY POTENT  IN-VITRO  METABOLISM  RISK   Superoxide flashes: Elemental events of mitochondrial ROS signaling in the heart 期刊论文 journal of molecular and cellular cardiology, 2012 Wang, Xianhua; Jian, Chongshu; Zhang, Xing; Huang, Zhanglong; Xu, Jiejia; Hou, Tingting; Shang, Wei; Ding, Yi; Zhang, Wanrui; Ouyang, Meng; Wang, Yuefan; Yang, Zhen; Zheng, Ming; Cheng, Heping 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/11 Superoxide flash  Mitochondria  Reactive oxygen species (ROS)  Mitochondrial permeability transition pore  Local ROS signaling  PERMEABILITY TRANSITION PORE  DEPENDENT ANION CHANNELS  CELL-DEATH  CYCLOPHILIN-D  CARDIAC MYOCYTES  OXIDATIVE-STRESS  ISOLATED HEPATOCYTES  MOLECULAR-MECHANISM  REPERFUSION INJURY  HYDROGEN-PEROXIDE   Regulation of the Arabidopsis anther transcriptome by DYT1 for pollen development 期刊论文 plant journal, 2012 Feng, Baomin; Lu, Dihong; Ma, Xuan; Peng, Yiben; Sun, Yujin; Ning, Gang; Ma, Hong 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/12 DYT1  anther development  tapetum  transcriptome  transcriptional regulation  binding site  ABORTED-MICROSPORES AMS  CELL FATE DETERMINATION  MALE-STERILITY  REPRODUCTIVE DEVELOPMENT  ENDOPLASMIC-RETICULUM  TAPETUM DEVELOPMENT  BRASSICA TAPETUM  NUCLEAR-PROTEIN  GENE-EXPRESSION  EXINE FORMATION