Investigation of brush-type chiral stationary phases based on O,O'-diaroyl tartardiamide and O,O'-bis-(arylcarbamoyl) tartardiamide

	Investigation of brush-type chiral stationary phases based on O,O'-diaroyl tartardiamide and O,O'-bis-(arylcarbamoyl) tartardiamide
	Wu, Haibo 1; Ji, Shuying 1; Yang, Bing 1; Yu, Hui 1; Jin, Yu 1; Ke, Yanxiong 1; Liang, Xinmiao 1,2
刊名	journal of separation science
	2012-02-01
卷号	35 期号:3 页码:351-358
关键词	Brush-type chiral stationary phase Chiral discrimination Chiral separation Tartaric acid derivatives
英文摘要	four chiral organosilanes based on o,o'-dibenzoyl tartardiamide, o,o'-bis-(3,5-dimethylbenzoyl) tartardiamide, o,o'-bis-(phenylcarbamoyl) tartardiamide and o,o'-bis-[(3,5-dimethylphenyl)carbamoyl] tartardiamide were synthesized and immobilized on silica to afford corresponding brush-type chiral stationary phases (csps) with well-defined structures. using 54 compounds containing a wide variety of structures as analytes, the enantioselectivities of the four csps were evaluated under normal-phase modes. 3,5-dimethyl substituent in the aryl group was found to significantly affect the enantioselectivity of csps containing aryl ester moieties. aryl carbamate moieties in csps were observed more beneficial for enantioseparation than aryl ester moieties. the additional hydrogen-bond donors (nh) present in the carbamate groups contributed greatly to the enantioselectivity of csps, which is contrary to the results that have been found in network-polymeric csps.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, analytical
研究领域[WOS]	chemistry
关键词[WOS]	performance liquid-chromatography ; tartaric acid ; resolution ; enantioseparation ; discrimination ; recognition ; enantiomers ; derivatives ; separation ; selectors
收录类别	SCI
语种	英语
WOS记录号	WOS:000299254000002
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/143076]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.E China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Minist Educ, Sch Pharm, Shanghai 200237, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China
推荐引用方式 GB/T 7714	Wu, Haibo,Ji, Shuying,Yang, Bing,et al. Investigation of brush-type chiral stationary phases based on O,O'-diaroyl tartardiamide and O,O'-bis-(arylcarbamoyl) tartardiamide[J]. journal of separation science,2012,35(3):351-358.
APA	Wu, Haibo.,Ji, Shuying.,Yang, Bing.,Yu, Hui.,Jin, Yu.,...&Liang, Xinmiao.(2012).Investigation of brush-type chiral stationary phases based on O,O'-diaroyl tartardiamide and O,O'-bis-(arylcarbamoyl) tartardiamide.journal of separation science,35(3),351-358.
MLA	Wu, Haibo,et al."Investigation of brush-type chiral stationary phases based on O,O'-diaroyl tartardiamide and O,O'-bis-(arylcarbamoyl) tartardiamide".journal of separation science 35.3(2012):351-358.