Femtosecond Laser-Induced Micropattern and Ca/P Deposition on Ti Implant Surface and Its Acceleration on Early Osseointegration

	Femtosecond Laser-Induced Micropattern and Ca/P Deposition on Ti Implant Surface and Its Acceleration on Early Osseointegration
	Liang, Chunyong 1; Wang, Hongshui 1; Yang, Jianjun 2; Cai, Yanli 1,3; Hu, Xin 4; Yang, Yang 2,5; Li, Baoe 1; Li, Hongjie 4; Li, Haipeng 1; Li, Changyi 4
刊名	acs applied materials & interfaces
	2013-08-28
卷号	5 期号:16 页码:8179-8186
关键词	femtosecond lasers Ti implant Ca/P phase micropatterning osseointegration
英文摘要	surface microstructure and chemical composition of the implant are very important for its osseointegration in vivo. in this paper, a hierarchical micropattern covered with calcium phosphate (ca/p phase) was obtained on titanium (ti) implant surface by femtosecond lasers (fsl) irradiation in hydroxyapatite suspension. the hierachical micropattern as well as ca/p phase increased osteoblastic cell adhesion. higher expression of osteogenic markers (osteocalcin, osteopontin, and runt related transcription factor-2) on the surface treated by fsl of 2.55 j/cm(2) indicated the favorable effect of laser treatment on cell differentiation. in vivo studies were carried out to evaluate the effect of laser treatment and ca/p deposition on the osseointegration. it showed that the binding capacity between bone and fsl-treated ti implants was obviously stronger than that between bone and polished or sand blasting and acid etching (sla) ti implants. bone trabecula surrounded the fsl-treated implants without fibrous tissue after 8-week implantation. also, higher bone mineral density was seen surrounding the fsl-treated implants. our in vitro and in vivo studies demonstrated that the fsl induced micropattern and ca/p phase had positive effects on the acceleration of early osseointegration of ti implants with bone tissue.
WOS标题词	science & technology ; technology
类目[WOS]	nanoscience & nanotechnology ; materials science, multidisciplinary
研究领域[WOS]	science & technology - other topics ; materials science
关键词[WOS]	titanium implants ; niti alloy ; in-vivo ; pulses ; osteointegration ; microstructures ; integration ; substrate ; ablation ; silicon
收录类别	SCI
语种	英语
WOS记录号	WOS:000323875800075
公开日期	2015-11-10
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/137810]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Hebei Univ Technol, Sch Mat Sci & Engn, Tianjin 300130, Peoples R China 2.Nankai Univ, Inst Modern Opt, Tianjin 300071, Peoples R China 3.Tianjin Univ, Sch Mat Sci & Engn, Tianjin 300072, Peoples R China 4.Tianjin Med Univ, Stomatol Hosp, Tianjin 300070, Peoples R China 5.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Liang, Chunyong,Wang, Hongshui,Yang, Jianjun,et al. Femtosecond Laser-Induced Micropattern and Ca/P Deposition on Ti Implant Surface and Its Acceleration on Early Osseointegration[J]. acs applied materials & interfaces,2013,5(16):8179-8186.
APA	Liang, Chunyong.,Wang, Hongshui.,Yang, Jianjun.,Cai, Yanli.,Hu, Xin.,...&Yang, Xianjin.(2013).Femtosecond Laser-Induced Micropattern and Ca/P Deposition on Ti Implant Surface and Its Acceleration on Early Osseointegration.acs applied materials & interfaces,5(16),8179-8186.
MLA	Liang, Chunyong,et al."Femtosecond Laser-Induced Micropattern and Ca/P Deposition on Ti Implant Surface and Its Acceleration on Early Osseointegration".acs applied materials & interfaces 5.16(2013):8179-8186.