Quantum dots encapsulated glycopolymer vesicles: Synthesis, lectin recognition and photoluminescent properties

	Quantum dots encapsulated glycopolymer vesicles: Synthesis, lectin recognition and photoluminescent properties
	Pei, Danfeng 1,2; Li, Yanchun 3; Huang, Qingrong 4; Ren, Qu 5; Li, Fan 1; Shi, Tongfei 1
刊名	COLLOIDS AND SURFACES B-BIOINTERFACES
	2015-03-01
卷号	127 页码:130-136
关键词	Glycopolymer vesicles RAFT polymerization Quantum dots Lectin recognition Targeted delivery Fluorescent imaging
英文摘要	Biomimetic star-shaped glycopolymer poly(epsilon-caprolactone)-b-poly(2-aminoethyl methacrylate-b-poly(gluconamidoethylmethacrylate) (SPCL-PAMA-PGAMA) was synthesized by the combination of ring opening polymerization (ROP) and reversible addition-fragmentation chain transfer (RAFT) polymerization. The glycopolymer self-assembled into vesicles with low critical aggregation concentration (CAC) (0.0075 mg/mL). Then, the carboxylic capped CdTe QDs were encapsulated within the glycopolymer vesicles. The QDs encapsulated glycopolymer vesicles (Gly@QDs vesicles) could specifically bind Concanavalin A (Con A) without changing the photoluminescent properties of the Gly@QDs vesicles. Cell viability studies revealed that the cytotoxicity of the Gly@QDs vesicles was remarkably improved as compared to that of the original QDs. The Gly@QDs vesicles were internalized by Hep G2 cells and then emitted green fluorescence in the cells. Consequently, these Gly@QDs vesicles provided a multifunctional platform for targeted delivery and imaging. (C) 2015 Elsevier B.V. All rights reserved.
收录类别	SCI
语种	英语
公开日期	2015-11-03
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/28540]
专题	化学研究所_高分子物理与化学实验室
作者单位	1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Univ Chinese Acad Sci, Being 100049, Peoples R China 3.Jilin Univ, Hosp 1, Dept Pediat Resp Med, Changchun 130021, Jilin Province, Peoples R China 4.Rutgers State Univ, Cook Coll, Dept Food Sci, New Brunswick, NJ 08901 USA 5.Air Force Gen Hosp, Clin Lab Ctr, Beijing 100142, Peoples R China
推荐引用方式 GB/T 7714	Pei, Danfeng,Li, Yanchun,Huang, Qingrong,et al. Quantum dots encapsulated glycopolymer vesicles: Synthesis, lectin recognition and photoluminescent properties[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2015,127:130-136.
APA	Pei, Danfeng,Li, Yanchun,Huang, Qingrong,Ren, Qu,Li, Fan,&Shi, Tongfei.(2015).Quantum dots encapsulated glycopolymer vesicles: Synthesis, lectin recognition and photoluminescent properties.COLLOIDS AND SURFACES B-BIOINTERFACES,127,130-136.
MLA	Pei, Danfeng,et al."Quantum dots encapsulated glycopolymer vesicles: Synthesis, lectin recognition and photoluminescent properties".COLLOIDS AND SURFACES B-BIOINTERFACES 127(2015):130-136.