Neural Correlates of Covert Face Processing: fMRI Evidence from a Prosopagnosic Patient

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	Neural Correlates of Covert Face Processing: fMRI Evidence from a Prosopagnosic Patient
	Liu, Jiangang 1; Wang, Meiyun 2; Shi, Xiaohong 2; Feng, Lu 3; Li, Ling 1; Thacker, Justine Marie 5; Tian, Jie3,4 ; Shi, Dapeng 2; Lee, Kang 5
刊名	CEREBRAL CORTEX
	2014-08-01
卷号	24 期号:8 页码:2081-2092
关键词	fMRI face processing fusiform gyrus prosopagnosia covert recognition
英文摘要	Brains can perceive or recognize a face even though we are subjectively unaware of the existence of that face. However, the exact neural correlates of such covert face processing remain unknown. Here, we compared the fMRI activities between a prosopagnosic patient and normal controls when they saw famous and unfamiliar faces. When compared with objects, the patient showed greater activation to famous faces in the fusiform face area (FFA) though he could not overtly recognize those faces. In contrast, the controls showed greater activation to both famous and unfamiliar faces in the FFA. Compared with unfamiliar faces, famous faces activated the controls', but not the patient's lateral prefrontal cortex (LPFC) known to be involved in familiar face recognition. In contrast, the patient showed greater activation in the bilateral medial frontal gyrus (MeFG). Functional connectivity analyses revealed that the patient's right middle fusiform gyrus (FG) showed enhanced connectivity to the MeFG, whereas the controls' middle FG showed enhanced connectivity to the LPFC. These findings suggest that the FFA may be involved in both covert and overt face recognition. The patient's impairment in overt face recognition may be due to the absence of the coupling between the right FG and the LPFC.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Neurosciences
研究领域[WOS]	Neurosciences & Neurology
关键词[WOS]	DISTRIBUTED CORTICAL NETWORK ; FUSIFORM GYRUS ; RECOGNITION ; PERCEPTION ; BRAIN ; AREA ; MEMORY ; LOBE ; DISSOCIATION ; INFORMATION
收录类别	SCI
语种	英语
WOS记录号	WOS:000340068500010
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/3995]
专题	自动化研究所_中国科学院分子影像重点实验室
作者单位	1.Beijing Jiaotong Univ, Sch Comp & Informat Technol, Beijing 100044, Peoples R China 2.Henan Prov Peoples Hosp, Zhengzhou 450003, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China 4.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Peoples R China 5.Univ Toronto, Dr Eric Jackman Inst Child Study, Toronto, ON M5R 2X2, Canada
推荐引用方式 GB/T 7714	Liu, Jiangang,Wang, Meiyun,Shi, Xiaohong,et al. Neural Correlates of Covert Face Processing: fMRI Evidence from a Prosopagnosic Patient[J]. CEREBRAL CORTEX,2014,24(8):2081-2092.
APA	Liu, Jiangang.,Wang, Meiyun.,Shi, Xiaohong.,Feng, Lu.,Li, Ling.,...&Lee, Kang.(2014).Neural Correlates of Covert Face Processing: fMRI Evidence from a Prosopagnosic Patient.CEREBRAL CORTEX,24(8),2081-2092.
MLA	Liu, Jiangang,et al."Neural Correlates of Covert Face Processing: fMRI Evidence from a Prosopagnosic Patient".CEREBRAL CORTEX 24.8(2014):2081-2092.