A trust region method in adaptive finite element framework for bioluminescence tomography
Zhang, Bo1; Yang, Xin2; Qin, Chenghu2; Liu, Dan2; Zhu, Shouping2; Feng, Jinchao3; Sun, Li3; Liu, Kai2; Han, Dong2; Ma, Xibo2
刊名OPTICS EXPRESS
2010-03-29
卷号18期号:7页码:6477-6491
英文摘要Bioluminescence tomography (BLT) is an effective molecular imaging (MI) modality. Because of the ill-posedness, the inverse problem of BLT is still open. We present a trust region method (TRM) for BLT source reconstruction. The TRM is applied in the source reconstruction procedure of BLT for the first time. The results of both numerical simulations and the experiments of cube phantom and nude mouse draw us to the conclusion that based on the adaptive finite element (AFE) framework, the TRM works in the source reconstruction procedure of BLT. To make our conclusion more reliable, we also compare the performance of the TRM and that of the famous Tikhonov regularization method after only one step of mesh refinement of the AFE framework. The conclusion is that the TRM can get faster and better results after only one mesh refinement step of AFE framework than the Tikhonov regularization method when handling large scale data. In the TRM, all the parameters are fixed, while in the Tikhonov method the regularization parameter needs to be well selected. (C) 2010 Optical Society of America
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Optics
研究领域[WOS]Optics
关键词[WOS]LIGHT ; RECONSTRUCTION ; TRANSPORT ; BOUNDARY ; TISSUES ; MEDIA
收录类别SCI
语种英语
WOS记录号WOS:000276602000007
内容类型期刊论文
源URL[http://ir.ia.ac.cn/handle/173211/3907]  
专题自动化研究所_中国科学院分子影像重点实验室
作者单位1.Northeastern Univ, Sino Dutch Biomed & Informat Engn Sch, Shenyang 110004, Peoples R China
2.Chinese Acad Sci, Inst Automat, Med Image Proc Grp, Beijing 100190, Peoples R China
3.Beijing Univ Technol, Dept Elect Informat & Control Engn, Beijing, Peoples R China
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GB/T 7714
Zhang, Bo,Yang, Xin,Qin, Chenghu,et al. A trust region method in adaptive finite element framework for bioluminescence tomography[J]. OPTICS EXPRESS,2010,18(7):6477-6491.
APA Zhang, Bo.,Yang, Xin.,Qin, Chenghu.,Liu, Dan.,Zhu, Shouping.,...&Tian, Jie.(2010).A trust region method in adaptive finite element framework for bioluminescence tomography.OPTICS EXPRESS,18(7),6477-6491.
MLA Zhang, Bo,et al."A trust region method in adaptive finite element framework for bioluminescence tomography".OPTICS EXPRESS 18.7(2010):6477-6491.
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