Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array

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	Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array
	Yang, Liu 2,3; Zhang, Kunlin1 ; Dai, Wei 2; He, Ximiao 1; Zhao, Qian 1; Wang, Jing1 ; Sun, Zhong Sheng 2
刊名	BMC GENOMICS
	2011-01-06
卷号	12
ISSN号	1471-2164
通讯作者	Wang, J (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
产权排序	1,2
英文摘要	Background: Recent progress in high-throughput technologies has greatly contributed to the development of DNA methylation profiling. Although there are several reports that describe methylome detection of whole genome bisulfite sequencing, the high cost and heavy demand on bioinformatics analysis prevents its extensive application. Thus, current strategies for the study of mammalian DNA methylomes is still based primarily on genome-wide methylated DNA enrichment combined with DNA microarray detection or sequencing. Methylated DNA enrichment is a key step in a microarray based genome-wide methylation profiling study, and even for future high-throughput sequencing based methylome analysis.
学科主题	Physiological psychology/Biological Psychology
收录类别	SCI
项目简介	This work was sponsored by the National High Technology Research and Development Program of China (863 Program) (Grant No. 2006AA02A304, to ZSS) from the Ministry of Science and Technology of the People's Republic of China; the National Natural Science Foundation of China (NSFC) (Grant No. 30221004, to ZSS); the Innovation Project of Chinese Academy of Sciences (KSCX2-YW-R-38, to ZSS); and Project for Young Scientists Fund, Institute of Psychology, Chinese Academy of Sciences (O9CX115011, to KZ). Funding to pay the Open Access publication charges for this article was also provided by the 863 grant. We thank Dr Laurie Goodman for her helpful suggestions to help us refine the manuscript. We also thank all staffs at Institute of Psychology, Chinese Academy of Sciences, for their sincere supports. We thank the anonymous reviewers for kind comments.
原文出处	http://www.biomedcentral.com/content/pdf/1471-2164-12-10.pdf
语种	英语
WOS记录号	WOS:000286425600001
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/13275]
专题	心理研究所_中国科学院心理健康重点实验室
作者单位	1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Behav Genet Ctr, Beijing 100101, Peoples R China 3.Zhejiang Univ, Sch Med, Hangzhou 310058, Zhejiang, Peoples R China
推荐引用方式 GB/T 7714	Yang, Liu,Zhang, Kunlin,Dai, Wei,et al. Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array[J]. BMC GENOMICS,2011,12.
APA	Yang, Liu.,Zhang, Kunlin.,Dai, Wei.,He, Ximiao.,Zhao, Qian.,...&Sun, Zhong Sheng.(2011).Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array.BMC GENOMICS,12.
MLA	Yang, Liu,et al."Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array".BMC GENOMICS 12(2011).