Establishment of widely expressed hb1f transgenic mouse lineage and its morphologic analysis

	Establishment of widely expressed hb1f transgenic mouse lineage and its morphologic analysis
	Wang, SL; He, Y; Xie, YH; Wang, Y; Li, JZ; Wang, L; Wang, ZG; Fu, JL
刊名	CHINESE SCIENCE BULLETIN
	2004
卷号	49 期号:2 页码:142-145
关键词	human B1 binding factor (hB1F) transgenic mouse lineage establishment phenotype analysis
通讯作者	Fu, JL (reprint author), Second Mil Med Univ, Dept Med Genet, Shanghai 200433, Peoples R China.,jlfu@guomai.sh.cn
英文摘要	Human nuclear receptor hB1F is a novel member of the fushi tarazu factor I subfamily of nuclear receptor superfamily. The studies about its homologous genes indicate that hB1F may play a key role in regulating the metabolic homeostasis of cholesterol. After obtaining the founder mice carrying the transgene of hb1f by microinjection, each founder was mated to normal C57 mouse and the positive F1 by PCR identification of the same founder were intercrossed within sisters and brothers to establish the transgenic mouse lineage. The results of F1, F2 and offspring of test cross identification showed that the widely expressed hb1f transgenic mouse lineage was established successfully in this study. The tissue morphology of the transgenic lineage was also analyzed preliminarily.
学科主题	Science & Technology - Other Topics
类目[WOS]	Multidisciplinary Sciences
关键词[WOS]	HEPATITIS-B-VIRUS ; FETOPROTEIN TRANSCRIPTION FACTOR ; ORPHAN NUCLEAR RECEPTOR ; ACID SYNTHESIS ; ENHANCER II ; GENE ; PROMOTER ; INTESTINE ; MICE ; FTF
收录类别	SCI
语种	英语
WOS记录号	WOS:000220239800007
内容类型	期刊论文
版本	出版稿
源URL	[http://202.127.25.143/handle/331003/2048]
专题	上海生化细胞研究所_上海生科院生化细胞研究所
推荐引用方式 GB/T 7714	Wang, SL,He, Y,Xie, YH,et al. Establishment of widely expressed hb1f transgenic mouse lineage and its morphologic analysis[J]. CHINESE SCIENCE BULLETIN,2004,49(2):142-145.
APA	Wang, SL.,He, Y.,Xie, YH.,Wang, Y.,Li, JZ.,...&Fu, JL.(2004).Establishment of widely expressed hb1f transgenic mouse lineage and its morphologic analysis.CHINESE SCIENCE BULLETIN,49(2),142-145.
MLA	Wang, SL,et al."Establishment of widely expressed hb1f transgenic mouse lineage and its morphologic analysis".CHINESE SCIENCE BULLETIN 49.2(2004):142-145.