Expression and secretion of functional recombinant(1) scu-PA : AV in insect cell using signal peptides
Huang, YH; Tian, RY; Hu, W; Wu, XF; Yang, SL; Gong, Y
刊名PROTEIN AND PEPTIDE LETTERS
2004
卷号11期号:1页码:49-55
关键词protein expression signal peptide baculovirus-insect cell system annexin V low molecular weight urokinase
通讯作者Huang, YH (reprint author), Chinese Acad Sci, Shanghai Res Ctr Biotechnol, Shanghai Inst Biol Sci, Shanghai 200233, Peoples R China.,xfwu@sunm.shcnc.ac.cn ; yigong@srcb.ac.cn
英文摘要A fusion protein (scu-PA:AV) was expressed in the baculovirus expression system and secreted from Sf9 cells lead by signal peptides, (2)mel and (3)egt. The scu-PA:AV displays both the urokinase activity and membrane binding activity of its parental components. Our work indicated that it is possible to be developed as a thrombus-targeting drug.
学科主题Biochemistry & Molecular Biology
类目[WOS]Biochemistry & Molecular Biology
关键词[WOS]PHOSPHOLIPID-BINDING ; PROTEIN ; PURIFICATION ; BACTERIAL ; ANTIBODY ; ANNEXINS ; CALCIUM ; GENE
收录类别SCI
语种英语
WOS记录号WOS:000220210400008
内容类型期刊论文
版本出版稿
源URL[http://202.127.25.143/handle/331003/2017]  
专题上海生化细胞研究所_上海生科院生化细胞研究所
推荐引用方式
GB/T 7714
Huang, YH,Tian, RY,Hu, W,et al. Expression and secretion of functional recombinant(1) scu-PA : AV in insect cell using signal peptides[J]. PROTEIN AND PEPTIDE LETTERS,2004,11(1):49-55.
APA Huang, YH,Tian, RY,Hu, W,Wu, XF,Yang, SL,&Gong, Y.(2004).Expression and secretion of functional recombinant(1) scu-PA : AV in insect cell using signal peptides.PROTEIN AND PEPTIDE LETTERS,11(1),49-55.
MLA Huang, YH,et al."Expression and secretion of functional recombinant(1) scu-PA : AV in insect cell using signal peptides".PROTEIN AND PEPTIDE LETTERS 11.1(2004):49-55.
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