Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter

	Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter
	Gao, DM; Wang, LF; Liu, J; Kong, YY; Wang, YA; Xie, YH
刊名	FEBS LETTERS
	2006
卷号	580 期号:7 页码:1702-1708
关键词	mLRH-1 transcript promoter embryogenesis
通讯作者	Xie, YH (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, State Key Lab Mol Biol, S212,Yueyang Rd 320, Shanghai 200031, Peoples R China.,yhxie@sibs.ac.cn
英文摘要	Liver receptor homologue 1 (LRH-1) plays important roles in many physiological processes and embryogenesis. However, little is known about the developmental regulation of lrh-1 expression. We identified a novel transcript of mouse lrh-1 (mlrh-1v2) from embryonic stem (ES) cells. mlrh-1v2 is expressed throughout embryogenesis and in several adult tissues, while the known transcript (mlrh-1v1) appears later during embryogenesis. mlrh-1v2 expression is directed by a new promoter which displays a strong activity in ES cells. The generation of the new transcript is conserved in rats. The identification of novel mlrh-1 variant and promoter is critical for elucidating LRH-1 functions in development and adult tissues. (c) 2006 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
学科主题	Biochemistry & Molecular Biology ; Biophysics ; Cell Biology
类目[WOS]	Biochemistry & Molecular Biology ; Biophysics ; Cell Biology
关键词[WOS]	LIVER RECEPTOR HOMOLOG-1 ; FETOPROTEIN TRANSCRIPTION FACTOR ; ORPHAN NUCLEAR RECEPTOR ; FACTOR FTF GENE ; REGULATES EXPRESSION ; LRH-1 ; AROMATASE ; PANCREAS ; HB1F
收录类别	SCI
语种	英语
WOS记录号	WOS:000236338300002
内容类型	期刊论文
版本	出版稿
源URL	[http://202.127.25.143/handle/331003/1745]
专题	上海生化细胞研究所_上海生科院生化细胞研究所
推荐引用方式 GB/T 7714	Gao, DM,Wang, LF,Liu, J,et al. Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter[J]. FEBS LETTERS,2006,580(7):1702-1708.
APA	Gao, DM,Wang, LF,Liu, J,Kong, YY,Wang, YA,&Xie, YH.(2006).Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter.FEBS LETTERS,580(7),1702-1708.
MLA	Gao, DM,et al."Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter".FEBS LETTERS 580.7(2006):1702-1708.