Zeolites Mn2+-NaY as oral gastrointestinal tract contrast agents in magnetic resonance imaging
Li Wei-Sheng; Li Zhong-Feng; Jing Feng-Ying; Yang Xiang-Guang; Li Xiao-Jing; Pei Feng-Kui; Wang Xu-Xia; Lei Hao
刊名ACTA CHIMICA SINICA
2007-09-28
卷号65期号:18页码:2029-2033
关键词magnetic resonance imaging NaY zeolite contrast agent relaxivity manganese(II)
英文摘要Mn2+ loaded zeolites were prepared by ion-exchange of NaY with MnCl2 and characterized by IR and XRD. The stability of MnNaY (3.2% Mn) at low pH and in the presence of metal ions at a concentration relevant to the gastrointestinal tract has been evaluated. The T-1-relaxivities of MnNaY decreased as the Mn2+ loading increased from 3.2% to 5.2%, with values ranging between 4.9 and 9.7 mmol center dot L-s(-1) at 400 MHz and 23 degrees C. T-1-weighted magnetic resonance imaging (MRI) of rats' abdomen showed a remarkable enhancement after oral administration of MnNaY (3.2% Mn). The results indicate that the MnNaY may be a potential gastrointestinal tract contrast agent for MRI.
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]MRI ; RELAXIVITY ; MANGANESE
收录类别SCI
语种英语
WOS记录号WOS:000249931300018
公开日期2015-08-18
内容类型期刊论文
源URL[http://ir.wipm.ac.cn/handle/112942/4918]  
专题武汉物理与数学研究所_2011年以前论文发表(包括2011年)
作者单位1.Chinese Acad Sci, Changchun Inst Appl Chem, Natl Res & Anal Ctr Electrochem & Spect, Green Chem & Proc Lab, Changchun 130022, Peoples R China
2.Chinese Acad Sci, Wuhan Inst Phys & Math, Lab Resonance & Atom & Mol Phys, Wuhan 430071, Peoples R China
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Li Wei-Sheng,Li Zhong-Feng,Jing Feng-Ying,et al. Zeolites Mn2+-NaY as oral gastrointestinal tract contrast agents in magnetic resonance imaging[J]. ACTA CHIMICA SINICA,2007,65(18):2029-2033.
APA Li Wei-Sheng.,Li Zhong-Feng.,Jing Feng-Ying.,Yang Xiang-Guang.,Li Xiao-Jing.,...&Lei Hao.(2007).Zeolites Mn2+-NaY as oral gastrointestinal tract contrast agents in magnetic resonance imaging.ACTA CHIMICA SINICA,65(18),2029-2033.
MLA Li Wei-Sheng,et al."Zeolites Mn2+-NaY as oral gastrointestinal tract contrast agents in magnetic resonance imaging".ACTA CHIMICA SINICA 65.18(2007):2029-2033.
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