Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity
	Tang,Jian-Jun ; Fang,Ping ; Xia,Hou-Lin ; Tu,Zheng-Chao ; Hou,Bi-Yu ; Yan,Yong-Ming ; Di,Lei ; Zhang,Li ; Cheng,Yong-Xian
刊名	FOOD RESEARCH INTERNATIONAL
	2015
卷号	67 页码:163-168
关键词	Polyrhachis dives Formicidae Chinese black ants Diabetic nephropathy Alkaloids
通讯作者	Zhang,L (reprint author),132 Lanhei Rd,Kunming 650201,Peoples R China. ; zhangli@imm.ac.cn ; yxcheng@mail.kib.ac.cn
英文摘要	Accumulated data have emphasized the critical role of inflammation in the pathogenesis of diabetic nephropathy (DN). Chinese black ants (Polyrhachis dives), an edible insect, are well-known for kidney tonifying and anti-inflammatory properties. We have conducted a study that led to isolation of thirteen nonpeptide nitrogen containing compounds from P. dives. Most of these substances possess pyridine moieties and three are alkaloids isolated for the first time from natural sources. Based on ethnopharmacological considerations, the biological potentials of these substances were determined utilizing multiple assays including renal protection, T-, B-lymphocyte proliferation, TNF-alpha, COX-1, COX-2, and Jak3 kinase inhibition. The finding that several members of this family display activities in one or more of these assays has led to the elucidation of part of the chemical profile of P. dives in terms of non-peptide, small-molecule components. (C) 2014 Elsevier Ltd. All rights reserved.
学科主题	Food Science & Technology
研究领域[WOS]	Food Science & Technology
关键词[WOS]	RHEUMATOID-ARTHRITIS ; IDENTIFICATION ; INHIBITION
收录类别	SCI
语种	英语
WOS记录号	WOS:000348619600019
公开日期	2015-07-07
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/20608]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Tang,Jian-Jun,Fang,Ping,Xia,Hou-Lin,et al. Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity[J]. FOOD RESEARCH INTERNATIONAL,2015,67:163-168.
APA	Tang,Jian-Jun.,Fang,Ping.,Xia,Hou-Lin.,Tu,Zheng-Chao.,Hou,Bi-Yu.,...&Cheng,Yong-Xian.(2015).Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity.FOOD RESEARCH INTERNATIONAL,67,163-168.
MLA	Tang,Jian-Jun,et al."Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity".FOOD RESEARCH INTERNATIONAL 67(2015):163-168.