Neural Basis of Emotional Decision Making in Trait Anxiety

CORC > 心理研究所 > 中国科学院心理研究所 > 中国科学院行为科学重点实验室

	Neural Basis of Emotional Decision Making in Trait Anxiety
	Xu, Pengfei 1; Gu, Ruolei2 ; Broster, Lucas S.3; Wu, Runguo 4; Van Dam, Nicholas T.5,6,7; Jiang, Yang 3; Fan, Jin 6,7,8,9; Luo, Yue-jia10
刊名	JOURNAL OF NEUROSCIENCE
	2013
卷号	33 期号:47 页码:18641-18653
ISSN号	0270-6474
通讯作者	Luo, YJ (reprint author), Shenzhen Univ, Inst Affect & Social Neurosci, Shenzhen 518060, Peoples R China.
产权排序	2
英文摘要	Although trait anxiety has been associated with risk decision making, whether it is related to risk per se or to the feeling of the risk, as well as the underlying neurocognitive mechanisms, remains unclear. Using a decision-making task with a manipulation of frame (i.e., written description of options as a potential gain or loss) and functional magnetic resonance imaging, we investigated the neurocognitive relationship between trait anxiety and decision making. The classic framing effect was observed: participants chose the safe option when it was described as a potential gain, but they avoided the same option when it was described as a potential loss. Most importantly, trait anxiety was positively correlated with this behavioral bias. Trait anxiety was also positively correlated with amygdala-based "emotional" system activation and its coupling with the ventromedial prefrontal cortex (vmPFC) when decisions were consistent with the framing effect, but negatively correlated with the dorsal anterior cingulate cortex (dACC)-based "analytic" system activation and its connectivity to the vmPFC when decisions ran counter to the framing effect. Our findings suggest that trait anxiety is not associated with subjective risk preference but an evaluative bias of emotional information in decision making, underpinned by a hyperactive emotional system and a hypoactive analytic system in the brain.
学科主题	Emotional psychology
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Neurosciences
研究领域[WOS]	Neurosciences & Neurology
关键词[WOS]	VENTROMEDIAL PREFRONTAL CORTEX ; FUNCTIONAL CONNECTIVITY MRI ; ANTERIOR CINGULATE CORTEX ; ORBITOFRONTAL CORTEX ; COGNITIVE CONTROL ; RISKY DECISIONS ; NEGATIVE AFFECT ; SUBJECT MOTION ; WORKING-MEMORY ; HEAD MOTION
收录类别	SCI
项目简介	This work was supported by the National Natural Science Foundation of China (31300847, 31300867, 30930031, and 91132704), the National Basic Research Program of China (973 Program, 2011 CB711000, 2014CB744600), United States National Institutes of Health (Grants 1R01TW007897, P50 DA005312, and T32 AG000242), the National Center for Research Resources (UL1RR033173), the National Center for Advancing Translational Sciences (UL1TR000117), and Scientific Foundation of Institute of Psychology, Chinese Academy of Sciences (Y2CQ013005). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. We thank Xiaosi Gu for offering helpful comments.
原文出处	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834062/pdf/zns18641.pdf
语种	英语
WOS记录号	WOS:000327449000027
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/10756]
专题	心理研究所_中国科学院行为科学重点实验室
作者单位	1.Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing 100875, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing 100101, Peoples R China 3.Univ Kentucky, Coll Med, Dept Behav Sci, Lexington, KY 40536 USA 4.Univ Edinburgh, Sch Social & Polit Sci, Edinburgh EH8 9LD, Midlothian, Scotland 5.NYU, Sch Med, Dept Psychiat, New York, NY 10016 USA 6.CUNY, Queens Coll, Dept Psychol, New York, NY 10075 USA 7.Mt Sinai Sch Med, Dept Psychiat, New York, NY 10029 USA 8.Mt Sinai Sch Med, Fishberg Dept Neurosci, New York, NY 10029 USA 9.Mt Sinai Sch Med, Friedman Brain Inst, New York, NY 10029 USA 10.Shenzhen Univ, Inst Affect & Social Neurosci, Shenzhen 518060, Peoples R China
推荐引用方式 GB/T 7714	Xu, Pengfei,Gu, Ruolei,Broster, Lucas S.,et al. Neural Basis of Emotional Decision Making in Trait Anxiety[J]. JOURNAL OF NEUROSCIENCE,2013,33(47):18641-18653.
APA	Xu, Pengfei.,Gu, Ruolei.,Broster, Lucas S..,Wu, Runguo.,Van Dam, Nicholas T..,...&Luo, Yue-jia.(2013).Neural Basis of Emotional Decision Making in Trait Anxiety.JOURNAL OF NEUROSCIENCE,33(47),18641-18653.
MLA	Xu, Pengfei,et al."Neural Basis of Emotional Decision Making in Trait Anxiety".JOURNAL OF NEUROSCIENCE 33.47(2013):18641-18653.