Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum
	Cheng, Yuan-Yuan 1,2; Chen, Huan 2,3; He, Hong-Ping 1; Zhang, Yu1 ; Li, Shi-Fei 1,2; Tang, Gui-Hua1,2 ; Guo, Ling-Li1 ; Yang, Wei 1,2; Zhu, Feng 1,2; Zheng, Yong-Tang 3
刊名	PHYTOCHEMISTRY
	2013-12-01
卷号	96 页码:360-369
关键词	Trigonostemon thyrsoideum Euphorbiaceae Daphnane diterpenoids Trigothysoids A-P Anti-HIV-1
英文摘要	Sixteen daphnane diterpenoids, trigothysoids A-P, along with 15 known ones, were isolated from the methanol extract of the twigs and leaves of Trigonostemon thy rsoideum. Their structures were established by extensive spectroscopic techniques, including 2D NMR spectroscopy and mass spectrometry. The anti-HIV-1 activity of the compounds was also evaluated in vitro, and five compounds demonstrated potent anti-HIV-1 activity, with EC50 values of 0.015-0.001 nM and TI values of 1618-17,619. (C) 2013 Elsevier Ltd. All rights reserved.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Biochemistry & Molecular Biology ; Plant Sciences
研究领域[WOS]	Biochemistry & Molecular Biology ; Plant Sciences
关键词[WOS]	IN-VITRO ; A-G ; REIDIOIDES ; POTENT ; CHINENSIS ; TRICHOSANTHIN ; CONSTITUENTS ; INHIBITORS ; REDIOCIDE ; HOWII
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000328869500038
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/19233]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China 3.Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Peoples R China
推荐引用方式 GB/T 7714	Cheng, Yuan-Yuan,Chen, Huan,He, Hong-Ping,et al. Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum[J]. PHYTOCHEMISTRY,2013,96:360-369.
APA	Cheng, Yuan-Yuan.,Chen, Huan.,He, Hong-Ping.,Zhang, Yu.,Li, Shi-Fei.,...&Hao, Xiao-Jiang.(2013).Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum.PHYTOCHEMISTRY,96,360-369.
MLA	Cheng, Yuan-Yuan,et al."Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum".PHYTOCHEMISTRY 96(2013):360-369.