Detection of trace microcystin-LR on a 20 MHz QCM sensor coated with in situ self-assembled MIPs

CORC > 长春光学精密机械与物理研究所 > 中国科学院长春光学精密机械与物理研究所 > 中科院长春光机所知识产出

	Detection of trace microcystin-LR on a 20 MHz QCM sensor coated with in situ self-assembled MIPs
	He H. ; Zhou L. ; Wang Y. ; Li C. ; Yao J. ; Zhang W. ; Zhang Q. ; Li M. ; Li H. ; Dong W.-F.
刊名	Talanta
	2014
期号	131 页码:8-13
ISSN号	ISBN/00399140
英文摘要	A 20 MHz quartz crystal microbalance (QCM) sensor coated with in situ self-assembled molecularly imprinted polymers (MIPs) was presented for the detection of trace microcystin-LR (MC-LR) in drinking water. The sensor performance obtained using the in situ self-assembled MIPs was compared with traditionally synthesized MIPs on 20 MHz and normal 10 MHz QCM chip. The results show that the response increases by more than 60% when using the in situ self-assembly method compared using the traditionally method while the 20 MHz QCM chip provides four-fold higher response than the 10 MHz one. Therefore, the in situ self-assembled MIPs coated on a high frequency QCM chip was used in the sensor performance test to detect MC-LR in tap water. It showed a limit of detection (LOD) of 0.04 nM which is lower than the safety guideline level (1 nM MC-LR) of drinking water in China. The low sensor response to other analogs indicated the high specificity of the sensor to MC-LR. The sensor showed high stability and low signal variation less than 2.58% after regeneration. The lake water sample analysis shows the sensor is possible for practical use. The combination of the higher frequency QCM with the in situ self-assembled MIPs provides a good candidate for the detection of other small molecules. 2014 Elsevier B.V. All rights reserved.
收录类别	EI
语种	英语
内容类型	期刊论文
源URL	[http://ir.ciomp.ac.cn/handle/181722/43886]
专题	长春光学精密机械与物理研究所_中科院长春光机所知识产出
推荐引用方式 GB/T 7714	He H.,Zhou L.,Wang Y.,et al. Detection of trace microcystin-LR on a 20 MHz QCM sensor coated with in situ self-assembled MIPs[J]. Talanta,2014(131):8-13.
APA	He H..,Zhou L..,Wang Y..,Li C..,Yao J..,...&Dong W.-F..(2014).Detection of trace microcystin-LR on a 20 MHz QCM sensor coated with in situ self-assembled MIPs.Talanta(131),8-13.
MLA	He H.,et al."Detection of trace microcystin-LR on a 20 MHz QCM sensor coated with in situ self-assembled MIPs".Talanta .131(2014):8-13.