Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification

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	Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification
	Ouyang, XY ; Li, J ; Liu, HJ ; Zhao, B ; Yan, J ; He, DN ; Fan, CH ; Chao, J
刊名	METHODS
	2014
卷号	67 期号:2 页码:198—204
关键词	BACTERIAL-DNA INTRACELLULAR DELIVERY GOLD NANOPARTICLES CPG MOTIFS PLATFORM NANOSTRUCTURES TRANSPORT ORIGAMI CARRIER OLIGONUCLEOTIDE
ISSN号	1046-2023
通讯作者	fchh@sinap.ac.cn ; chaojie@sinap.ac.cn
英文摘要	DNA nanostructures have recently emerged as a type of drug delivery nanocarriers due to their suitable sizes, well-defined structures and low-toxicity. Here, we present a protocol for the assembly of DNA nanoribbon structures with rolling circle amplification (RCA) and delivery of CpG oligonucleotide. DNA nanoribbons with different dimensions and patterns were assembled with long RCA strands and several short staples. Significantly, we demonstrated they exhibited high-efficiency cellular uptake and improved immunostimulatory activity compared with ss- or ds- DNA. (C) 2013 Elsevier Inc. All rights reserved.
收录类别	SCI
语种	英语
WOS记录号	WOS:000335623900013
公开日期	2015-03-13
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/14381]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
推荐引用方式 GB/T 7714	Ouyang, XY,Li, J,Liu, HJ,et al. Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification[J]. METHODS,2014,67(2):198—204.
APA	Ouyang, XY.,Li, J.,Liu, HJ.,Zhao, B.,Yan, J.,...&Chao, J.(2014).Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification.METHODS,67(2),198—204.
MLA	Ouyang, XY,et al."Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification".METHODS 67.2(2014):198—204.