A Connectome Computation System for discovery science of brain

	A Connectome Computation System for discovery science of brain
	Xi-Nian Zuo; Zhi Yang; Lili Jiang; Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo
刊名	Science Bulletin
	2015
通讯作者邮箱	zuoxn@psych.ac.cn
卷号	60 期号:1 页码:86-95
关键词	Connectome Life span Big data Normative charts Discovery science
通讯作者	Xi-Nian Zuo
产权排序	1
合作状况	国内
中文摘要	Much like genomics, brain connectomics has rapidly become a core component of most national brain projects around the world. Beyond the ambitious aims of these projects, a fundamental challenge is the need for an efficient, robust, reliable and easy-to-use pipeline to mine such large neuroscience datasets. Here, we introduce a computational pipeline—namely the Connectome Computation System (CCS)—for discovery science of human brain connectomes at the macroscale with multimodal magnetic resonance imaging technologies. The CCS is designed with a three-level hierarchical structure that includes data cleaning and preprocessing, individual connectome mapping and connectome mining, and knowledge discovery. Several functional modules are embedded into this hierarchy to implement quality control procedures, reliability analysis and connectome visualization. We demonstrate the utility of the CCS based upon a publicly available dataset, the NKI–Rockland Sample, to delineate the normative trajectories of well-known large-scale neural networks across the natural life span (6–85 years of age). The CCS has been made freely available to the public via GitHub (https://github.com/zuoxinian/CCS) and our laboratory’s Web site (http://lfcd.psych.ac.cn/ccs.html) to facilitate progress in discovery science in the field of human brain connectomics.
学科主题	认知神经科学
收录类别	SCI
资助信息	National Basic Research Program; National Natural Science Foundation of China; Chinese Academy of Sciences
原文出处	http://link.springer.com/article/10.1007/s11434-014-0698-3
语种	英语
公开日期	2015-01-14
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/10184]
专题	心理研究所_认知与发展心理学研究室
通讯作者	Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo; Xi-Nian Zuo
推荐引用方式 GB/T 7714	Xi-Nian Zuo,Zhi Yang,Lili Jiang,et al. A Connectome Computation System for discovery science of brain[J]. Science Bulletin,2015,60(1):86-95.
APA	Xi-Nian Zuo.,Zhi Yang.,Lili Jiang.,Xi-Nian Zuo.,Xi-Nian Zuo.,...&Xi-Nian Zuo.(2015).A Connectome Computation System for discovery science of brain.Science Bulletin,60(1),86-95.
MLA	Xi-Nian Zuo,et al."A Connectome Computation System for discovery science of brain".Science Bulletin 60.1(2015):86-95.