Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study

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	Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study
	[Cai Bingna ; Pan Jianyu ; Wan Peng ; Sun Huili] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China ; [Wu Yuantao] Chinese Acad Sci, Bur Sci & Technol Resource & Environm, Beijing 100864, Peoples R China ; [Cai Bingna ; Wan Peng ; Sun Huili] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
刊名	CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
	2013
卷号	31 期号:4 页码:813-820
关键词	marine protein oyster peptides enteral nutrition formula immunomodulation
ISSN号	0254-4059
通讯作者	shl@scsio.ac.cn
中文摘要	Oyster peptides were produced from Crassostrea hongkongensis and used as a new protein source for the preparation of an oyster peptide-based enteral nutrition formula (OPENF). Reserpineinduced malabsorption mice and cyclophosphamide-induced immunosuppression mice were used in this study. OPENF powder is light yellow green and has a protein-fat-carbohydrate ratio of 16:9:75 with good solubility in water. A pilot study investigating immune functional impacts of the OPENF on mice show that the OPENF enhanced spleen lymphocyte proliferation and the activity of natural killer (NK) cells in BALB/c mice. Furthermore, OPENF can improve intestinal absorption, increase food utilization ratio, and maintain the normal physiological function of mice. These results suggest that oyster peptides could serve as a new protein source for use in enteral nutrition formula, but more importantly, also indicate that OPENF has an immunostimulating effect in mice.
学科主题	Limnology ; Oceanography
资助信息	Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX2-EW-Q214), the Comprehensive Strategic Cooperation Programs between Guangdong Province and Chinese Academy of Sciences (Nos. 2011A090100008, 2009B091300018, 2010B090300027), and the Marine Fisheries Technology Promotion Special Program of Guangdong Province (No. A2009009-035(a))
原文出处	SCIENCE PRESS
语种	英语
WOS记录号	WOS:000321629400012
公开日期	2015-01-22
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/11013]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
推荐引用方式 GB/T 7714	[Cai Bingna,Pan Jianyu,Wan Peng,et al. Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2013,31(4):813-820.
APA	[Cai Bingna.,Pan Jianyu.,Wan Peng.,Sun Huili] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China.,[Wu Yuantao] Chinese Acad Sci, Bur Sci & Technol Resource & Environm, Beijing 100864, Peoples R China.,...&Sun Huili] Univ Chinese Acad Sci, Beijing 100049, Peoples R China.(2013).Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,31(4),813-820.
MLA	[Cai Bingna,et al."Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 31.4(2013):813-820.