Indimicins A-E, Bisindole Alkaloids from the Deep-Sea-Derived Streptomyces sp SCSIO 03032

CORC > 南海海洋研究所 > 中国科学院南海海洋研究所 > 中科院海洋生物资源可持续利用重点实验室

	Indimicins A-E, Bisindole Alkaloids from the Deep-Sea-Derived Streptomyces sp SCSIO 03032
	Zhang, WJ ; Ma, L ; Li, SM ; Liu, Z ; Chen, YC ; Zhang, HB ; Zhang, GT ; Zhang, QB ; Tian, XP ; Yuan, CS ; Zhang, S ; Zhang, WM ; Zhang, CS
刊名	JOURNAL OF NATURAL PRODUCTS
	2014
卷号	77 期号:8 页码:1887-1892
ISSN号	0163-3864
通讯作者	czhang2006@gmail.com
中文摘要	Five new bisindole alkaloids, indimicins A-E (1-5), bearing a unique 1',3'-dimethyl-2'-hydroindole moiety, were isolated from the marine-derived Streptomyces sp. SCSIO 03032, along with two new compounds, lynamicins F and G (6 and 7). Their planar structures were elucidated by detailed interpretation of their MS and NMR spectroscopic data, and the absolute configurations were determined by X-ray crystallographic analysis (for 1), comparison of CD spectra (for 2-4), and quantum chemical calculations (for 5). Indimicin B (2) exhibited moderate cytotoxic activity toward the MCF-7 cell line.
学科主题	Plant Sciences ; Pharmacology & Pharmacy
收录类别	SCI
资助信息	MOST [2010CB833805, 2012AA092104]; Strategic Priority Research Program of the Chinese Academy of Sciences [XDA11030403]; NSFC [31125001, 41106143, 41206138, 31290233]; Administration of Ocean and Fisheries of Guangdong Province [GD2012-D01-002]
原文出处	AMER CHEMICAL SOC
WOS记录号	WOS:000340861800017
公开日期	2014-12-11
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/10411]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
推荐引用方式 GB/T 7714	Zhang, WJ,Ma, L,Li, SM,et al. Indimicins A-E, Bisindole Alkaloids from the Deep-Sea-Derived Streptomyces sp SCSIO 03032[J]. JOURNAL OF NATURAL PRODUCTS,2014,77(8):1887-1892.
APA	Zhang, WJ.,Ma, L.,Li, SM.,Liu, Z.,Chen, YC.,...&Zhang, CS.(2014).Indimicins A-E, Bisindole Alkaloids from the Deep-Sea-Derived Streptomyces sp SCSIO 03032.JOURNAL OF NATURAL PRODUCTS,77(8),1887-1892.
MLA	Zhang, WJ,et al."Indimicins A-E, Bisindole Alkaloids from the Deep-Sea-Derived Streptomyces sp SCSIO 03032".JOURNAL OF NATURAL PRODUCTS 77.8(2014):1887-1892.