First way of enantioselective synthesis of moxifloxacin intermediate
Li GuangXun ; Wu Lei ; Fu QingQuan ; Tang Zhuo ; Zhang XiaoMei
刊名SCIENCE CHINA-CHEMISTRY
2013
卷号56期号:3页码:307-311
关键词enantioselective synthesis (S moxifloxacin intermediate S)-2 8-diazobicyclo [4.3.0] nonane
ISSN号1674-7291
通讯作者Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Peoples R China ; Zhang XiaoMei
产权排序1
英文摘要A new method of enantioselective synthesis of (S,S)-2,8-diazobicyclo [4.3.0] nonane was found by using (R)-2-amino-2- phenyl-ethanol as chiral induction reagent. The entire synthetic process included 8 steps which were easy to operate with high yield. The purification method was only simple recrystallization or even used directly in the next step without further purification. The total yield was 29%.
学科主题Chemistry
收录类别SCI
语种英语
WOS记录号WOS:000314890600007
公开日期2014-11-21
内容类型期刊论文
源URL[http://210.75.237.14/handle/351003/24175]  
专题成都生物研究所_天然产物研究
推荐引用方式
GB/T 7714
Li GuangXun,Wu Lei,Fu QingQuan,et al. First way of enantioselective synthesis of moxifloxacin intermediate[J]. SCIENCE CHINA-CHEMISTRY,2013,56(3):307-311.
APA Li GuangXun,Wu Lei,Fu QingQuan,Tang Zhuo,&Zhang XiaoMei.(2013).First way of enantioselective synthesis of moxifloxacin intermediate.SCIENCE CHINA-CHEMISTRY,56(3),307-311.
MLA Li GuangXun,et al."First way of enantioselective synthesis of moxifloxacin intermediate".SCIENCE CHINA-CHEMISTRY 56.3(2013):307-311.
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