Cytotoxic Phorbol Esters of Croton tiglium

	Cytotoxic Phorbol Esters of Croton tiglium
	Zhang, Xiao-Long ; Wang, Lun ; Li, Fu ; Yu, Kai ; Wang, Ming-Kui
刊名	JOURNAL OF NATURAL PRODUCTS
	2013
卷号	76 期号:5 页码:858-864
ISSN号	0163-3864
通讯作者	Wang, MK (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Key Lab Sichuan Prov, Key Lab Mt Ecol Restorat & Bioresource Utilizat &, Chengdu 610041, Peoples R China.
产权排序	1
英文摘要	Chemical investigation of the seeds of Croton tiglium afforded eight new phorbol diesters (three phorbol diesters, 1-3, and five 4-deoxy-4 alpha-phorbol diesters, 4-8), together with 11 known phorbol diesters (nine phorbol diesters, 9-17, and two 4-deoxy-4 alpha-phorbol diesters, 18 and 19). The structures of compounds 1-8 were determined by spectroscopic data information and chemical degradation experiments. The cytotoxic activities of the phorbol diesters were evaluated against the SNU387 hepatic tumor cell line, and compound 3 exhibited the most potent activity (IC50 1.2 mu M).
学科主题	Plant Sciences; Pharmacology & Pharmacy
收录类别	SCI
语种	英语
WOS记录号	WOS:000319650600007
公开日期	2014-11-21
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/24170]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Zhang, Xiao-Long,Wang, Lun,Li, Fu,et al. Cytotoxic Phorbol Esters of Croton tiglium[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(5):858-864.
APA	Zhang, Xiao-Long,Wang, Lun,Li, Fu,Yu, Kai,&Wang, Ming-Kui.(2013).Cytotoxic Phorbol Esters of Croton tiglium.JOURNAL OF NATURAL PRODUCTS,76(5),858-864.
MLA	Zhang, Xiao-Long,et al."Cytotoxic Phorbol Esters of Croton tiglium".JOURNAL OF NATURAL PRODUCTS 76.5(2013):858-864.