Identification and expression profiles of prdm1 in medaka Oryzias latipes

CORC > 水生生物研究所 > 鱼类生物学及渔业生物技术研究中心 > 期刊论文

	Identification and expression profiles of prdm1 in medaka Oryzias latipes
	Zhao, Haobin 1,2; Zhang, Xiaosha 1; Cheng, Nana 1; Duan, Jundan 1; Wang, Jialin 1; Nagahama, Yoshitaka 2,3; Zhong, Xueping 1; Zhou, Qingchun 1; Wang, Yaping 4
刊名	MOLECULAR BIOLOGY REPORTS
	2014-02-01
卷号	41 期号:2 页码:617-626
关键词	Medaka Zebrafish Prdm1a Prdm1b Embryogenesis Gene expression Immune response
ISSN号	0301-4851
通讯作者	Zhao, HB (reprint author), Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
中文摘要	Mouse Prdm1, also known as Blimp1, plays important roles in maturation and survival of lymphoid cells, as well as in organogenesis of muscle, limb, sensor organs and primordial germ cells. The homologues of mouse prdm1 have been identified in a diverse of animals including zebrafish and fugu. Here, we report the identification and expression profiles of two homologues of prdm1, namely prdm1a and prdm1b in medaka, Oryzias latipes. The transcripts of prdm1a and prdm1b were detectable in all the tissues including immune organs such as gill, spleen, kidney, liver and intestine that we have checked on. The transcripts of prdm1a could be detected in the embryonic shield at mid-gastrula stage and later in the somite, eye, otic vesicle, branchial arches, fin, intestine and cloaca during embryogenesis using in situ hybridization. Moreover, the expression of prdm1a in the liver of both medaka and zebrafish could be up-regulated by the immune stimuli including lipopolysaccharide, polyI:C and the grass carp reovirus, similarly to the up-regulation of IL1B. These results indicate that Prdm1a may play important roles in embryogenesis and also in immune response in fish.
英文摘要	Mouse Prdm1, also known as Blimp1, plays important roles in maturation and survival of lymphoid cells, as well as in organogenesis of muscle, limb, sensor organs and primordial germ cells. The homologues of mouse prdm1 have been identified in a diverse of animals including zebrafish and fugu. Here, we report the identification and expression profiles of two homologues of prdm1, namely prdm1a and prdm1b in medaka, Oryzias latipes. The transcripts of prdm1a and prdm1b were detectable in all the tissues including immune organs such as gill, spleen, kidney, liver and intestine that we have checked on. The transcripts of prdm1a could be detected in the embryonic shield at mid-gastrula stage and later in the somite, eye, otic vesicle, branchial arches, fin, intestine and cloaca during embryogenesis using in situ hybridization. Moreover, the expression of prdm1a in the liver of both medaka and zebrafish could be up-regulated by the immune stimuli including lipopolysaccharide, polyI:C and the grass carp reovirus, similarly to the up-regulation of IL1B. These results indicate that Prdm1a may play important roles in embryogenesis and also in immune response in fish.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Biochemistry & Molecular Biology
研究领域[WOS]	Biochemistry & Molecular Biology
关键词[WOS]	INDUCED MATURATION PROTEIN-1 ; TRANSCRIPTIONAL REPRESSOR BLIMP1/PRDM1 ; SECRETING PLASMA-CELLS ; TUMOR-SUPPRESSOR GENE ; PRIMORDIAL GERM-CELLS ; B-CELL ; BLIMP-1 EXPRESSION ; NEURAL CREST ; DIFFERENTIATION ; LYMPHOCYTES
收录类别	SCI
资助信息	National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science
语种	英语
WOS记录号	WOS:000330860900006
公开日期	2014-08-08
内容类型	期刊论文
源URL	[http://ir.ihb.ac.cn/handle/342005/20051]
专题	水生生物研究所_鱼类生物学及渔业生物技术研究中心_期刊论文
作者单位	1.Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China 2.Japan Soc Promot Sci, Tokyo 1028471, Japan 3.Ehime Univ, Inst Collaborat Relat, Matsuyama, Ehime 7908577, Japan 4.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Fresh Water Ecol & Biotechnol, Wuhan 430074, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Haobin,Zhang, Xiaosha,Cheng, Nana,et al. Identification and expression profiles of prdm1 in medaka Oryzias latipes[J]. MOLECULAR BIOLOGY REPORTS,2014,41(2):617-626.
APA	Zhao, Haobin.,Zhang, Xiaosha.,Cheng, Nana.,Duan, Jundan.,Wang, Jialin.,...&Wang, Yaping.(2014).Identification and expression profiles of prdm1 in medaka Oryzias latipes.MOLECULAR BIOLOGY REPORTS,41(2),617-626.
MLA	Zhao, Haobin,et al."Identification and expression profiles of prdm1 in medaka Oryzias latipes".MOLECULAR BIOLOGY REPORTS 41.2(2014):617-626.