| 6(1)-O-Caffeoylarbutin inhibits melanogenesis in zebrafish | |
Xu, Min1; Lao, Qiao-Cong2; Zhao, Ping3; Zhu, Xiao-Yu2; Zhu, Hong-Tao1; Luo, Xu-Lu3; Yang, Chong-Ren1; He, Jian-Hui2; Li, Chun-Qi2,4; Zhang, Ying-Jun1
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| 刊名 | NATURAL PRODUCT RESEARCH
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| 2014-06-18 | |
| 卷号 | 28期号:12页码:932-934 |
| 关键词 | 6-O-caffeoylarbutin anti-melanogenic Vaccinium dunalianum |
| ISSN号 | 1478-6419 |
| 通讯作者 | Zhao,P (reprint author),Southwest Forestry Univ,Key Lab Forest Resources Conservat & Use Southwes,Minist Educ,Kunming 650224,Peoples R China. |
| 英文摘要 | 6-O-Caffeoylarbutin, an arbutin derivative, is a naturally occurring glucoside of hydroquinone from Vaccinium dunalianum. On anti-melanogenic effect assay, 6-O-caffeoylarbutin expressed a stronger anti-melanin activity in a dose-dependent manner with about a two-fold more than that of arbutin, but with less toxicity about a two-fold lower than that of arbutin. In addition, melanin synthesis could be fully recovered after the removal of 6-O-caffeoylarbutin. The result suggested that 6-O-caffeoylarbutin could be a candidate natural product to serve as a skin-whitening ingredient with the merits of potent melanin inhibition, less toxicity and reversible melanin synthesis after stopping use. |
| 学科主题 | Chemistry ; Pharmacology & Pharmacy |
| 类目[WOS] | Chemistry, Applied ; Chemistry, Medicinal |
| 研究领域[WOS] | Chemistry ; Pharmacology & Pharmacy |
| 关键词[WOS] | DEOXYARBUTIN ; SAFETY |
| 收录类别 | SCI |
| 资助信息 | NSFC [21062018]; 973 Program of Science and Technology of the People's Republic of China [2011CB915503]; Fourteenth Batch Candidates of the Young Academic Leaders of Yunnan Province [2011CI044]; West Light Foundation of the Chinese Academy of Sciences; Scientific Research Foundation (SRF) for the Returned Overseas Chinese Scholars (ROCS), State Education Ministry (SEM) |
| 语种 | 英语 |
| WOS记录号 | WOS:000335848500014 |
| 公开日期 | 2014-06-23 |
| 内容类型 | 期刊论文 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/18101]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Hunter Biotechnol Inc, Transfarland, Xiaoshan Econ & Technol Dev Zone, Hangzhou 311231, Zhejiang, Peoples R China 3.Southwest Forestry Univ, Key Lab Forest Resources Conservat & Use Southwes, Minist Educ, Kunming 650224, Peoples R China 4.Wenzhou Med Univ, Zhejiang Prov Key Lab Technol & Applicat Model Or, Wenzhou 325035, Zhejiang, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Min,Lao, Qiao-Cong,Zhao, Ping,et al. 6(1)-O-Caffeoylarbutin inhibits melanogenesis in zebrafish[J]. NATURAL PRODUCT RESEARCH,2014,28(12):932-934. |
| APA | Xu, Min.,Lao, Qiao-Cong.,Zhao, Ping.,Zhu, Xiao-Yu.,Zhu, Hong-Tao.,...&Zhang, Ying-Jun.(2014).6(1)-O-Caffeoylarbutin inhibits melanogenesis in zebrafish.NATURAL PRODUCT RESEARCH,28(12),932-934. |
| MLA | Xu, Min,et al."6(1)-O-Caffeoylarbutin inhibits melanogenesis in zebrafish".NATURAL PRODUCT RESEARCH 28.12(2014):932-934. |
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