Synthesis of Neu5Ac-alpha-C-galactopyranosyl-functionalized magnetic nanoparticles via click chemistry
Zhang, Chaoli ; Ma, Xing ; Du, Yuguo
刊名TETRAHEDRON
2013
卷号69期号:35页码:7300-7307
通讯作者Du, YG
中文摘要A new type of glyco-nanoparticle has been accomplished through Cu(I)-catalyzed 1,3-dipolar cycloaddition of 6-azidohexyl Neu5Ac-alpha-C-galactoside and N-propargyl derivative, which was attached on a silica-wrapping magnetic nanoparticle. Neu5Ac-alpha-C-galactoside was stereo-selectively synthesized in 11 steps from isopropyl thiogalactopyranoside and per-acetylated Neu5Ac phenylsulfone using samarium-mediated reductive desulfonylation as the key step. Magnetic nanoparticles were prepared with one-step hydrothermal method and a subsequent coating with (N,N'-di-propargyl-3-aminopropyol) triethoxysilane derivative. (C) 2013 Elsevier Ltd. All rights reserved.
收录类别SCI
WOS记录号WOS:000322557500014
公开日期2014-06-06
内容类型期刊论文
源URL[http://ir.rcees.ac.cn/handle/311016/7475]  
专题生态环境研究中心_环境化学与生态毒理学国家重点实验室
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GB/T 7714
Zhang, Chaoli,Ma, Xing,Du, Yuguo. Synthesis of Neu5Ac-alpha-C-galactopyranosyl-functionalized magnetic nanoparticles via click chemistry[J]. TETRAHEDRON,2013,69(35):7300-7307.
APA Zhang, Chaoli,Ma, Xing,&Du, Yuguo.(2013).Synthesis of Neu5Ac-alpha-C-galactopyranosyl-functionalized magnetic nanoparticles via click chemistry.TETRAHEDRON,69(35),7300-7307.
MLA Zhang, Chaoli,et al."Synthesis of Neu5Ac-alpha-C-galactopyranosyl-functionalized magnetic nanoparticles via click chemistry".TETRAHEDRON 69.35(2013):7300-7307.
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