Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli

CORC > 青岛生物能源与过程研究所 > 中国科学院青岛生物能源与过程研究所 > 材料生物技术研究中心

	Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli
	Zheng, Yan-Ning 1,2; Li, Ling-Ling 1,3; Liu, Qiang 1,3; Yang, Jian-Ming 1,2; Wang, Xiang-Wei 1,2; Liu, Wei 1; Xu, Xin 1; Liu, Hui 1; Zhao, Guang 1; Xian, Mo1
刊名	MICROBIAL CELL FACTORIES
	2012-05-20
卷号	11 期号:1 页码:65
关键词	Fatty alcohol Escherichia coli Pathway optimization Selective production Fermentation
英文摘要	Background: With the increasing stress from oil price and environmental pollution, aroused attention has been paid to the microbial production of chemicals from renewable sources. The C12/14 and C16/18 alcohols are important feedstocks for the production of surfactants and detergents, which are widely used in the most respected consumer detergents, cleaning products and personal care products worldwide. Though bioproduction of fatty alcohols has been carried out in engineered E. coli, several key problems have not been solved in earlier studies, such as the quite low production of C16/18 alcohol, the lack of optimization of the fatty alcohol biosynthesis pathway, and the uncharacterized performance of the engineered strains in scaled-up system.
学科主题	生物基化学品
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Biotechnology & Applied Microbiology
研究领域[WOS]	Biotechnology & Applied Microbiology
关键词[WOS]	CARRIER PROTEIN THIOESTERASE ; COENZYME-A REDUCTASE ; ACYL-COENZYME ; PERIPLASMIC ENZYME ; ACID SYNTHESIS ; CHAIN ; GENE ; OVERPRODUCTION ; PURIFICATION ; SPECIFICITY
收录类别	SCI
语种	英语
WOS记录号	WOS:000308752000001
公开日期	2014-03-27
内容类型	期刊论文
源URL	[http://ir.qibebt.ac.cn:8080/handle/337004/1754]
专题	青岛生物能源与过程研究所_材料生物技术研究中心
作者单位	1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao Laoshan Dist 266101, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Sichuan Agr Univ, Coll Food Sci, Yaan 625014, Peoples R China
推荐引用方式 GB/T 7714	Zheng, Yan-Ning,Li, Ling-Ling,Liu, Qiang,et al. Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli[J]. MICROBIAL CELL FACTORIES,2012,11(1):65.
APA	Zheng, Yan-Ning.,Li, Ling-Ling.,Liu, Qiang.,Yang, Jian-Ming.,Wang, Xiang-Wei.,...&Xian, Mo.(2012).Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli.MICROBIAL CELL FACTORIES,11(1),65.
MLA	Zheng, Yan-Ning,et al."Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli".MICROBIAL CELL FACTORIES 11.1(2012):65.