GRAFTING POLYMERIZATION OF L-LACTIDE ON HYDROXYAPATITE NANOPARTICLES

	GRAFTING POLYMERIZATION OF L-LACTIDE ON HYDROXYAPATITE NANOPARTICLES
	Song XF ; Ling FG ; Chen XS
刊名	acta polymerica sinica
	2013
期号	1 页码:95-101
关键词	SURFACE MODIFICATION ACID
ISSN号	1000-3304
通讯作者	song xf
中文摘要	poly(lactid-glycolide acid)/hydroxyapatite (plga/ha) materials, as a class of composites,which have good bioactivity, absorbability and biodegradability, show promising applications in biomedical and tissue engineering fields. to improve the compatibility of ha and plga, the ring-opening polymerizations of l-lactic acid on three types of ha surfaces with different surface hydroxyl functionality : unmodified ha, ha modified with l-lactic acid, and ha modified with hexamethylene diisocyanate tethered ethylene glycol were carried out to produce poly(l-lactide acid) grafted hydroxyapatite (plla-g-ha). the results of ftir, xps, tem and tga show that plla was successfully grafted onto surface of ha by the above three methods. and the grafting rate of plla was dependent on the nature and steric environment of the hydroxyl groups on the ha surfaces, among which ha modified with (hmdi + eg) presented the best grafting percentage of 25%. the proportional change between inorganic and organic phase brought about little influence on plla grafting rate. the plla-g-ha can stably disperse in chloroform over 2 days without deposition. to investigate practicability of the composites used as bone guided regeneration membranes, tensile test after co-electrospinning shows that plla-g-ha/ plag nanofibrous membrane has better mechanical performance compared to ha/plga membrane, and its tensile force reaches maximum at 5% filling content.
收录类别	SCI收录期刊论文
语种	中文
WOS记录号	WOS:000314263500014
公开日期	2014-04-16
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/50094]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Song XF,Ling FG,Chen XS. GRAFTING POLYMERIZATION OF L-LACTIDE ON HYDROXYAPATITE NANOPARTICLES[J]. acta polymerica sinica,2013(1):95-101.
APA	Song XF,Ling FG,&Chen XS.(2013).GRAFTING POLYMERIZATION OF L-LACTIDE ON HYDROXYAPATITE NANOPARTICLES.acta polymerica sinica(1),95-101.
MLA	Song XF,et al."GRAFTING POLYMERIZATION OF L-LACTIDE ON HYDROXYAPATITE NANOPARTICLES".acta polymerica sinica .1(2013):95-101.