ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora
	Wang Weiguang 1,2; Wu Haiyan 1; Du Xue 1; Yan Juming 1; Li Yan1 ; Pu Jianxin1 ; Sun Handong1
刊名	CHINESE JOURNAL OF CHEMISTRY
	2012-06-01
卷号	30 期号:6 页码:1226-1230
关键词	ent-Kaurane diterpenoid Isodon structure elucidation cytotoxicity
ISSN号	1001-604X
通讯作者	Pu, JX (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kuming 650201, Yunan, Peoples R China,pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
英文摘要	Four new ent-kaurane diterpenoids, 6 beta,13a,15 beta-trihydroxy-16-ene-3a,20-epoxy-ent-kaur-1,7-dione (1), 6-hydroxy-3a,20-epoxy-5(6)-ene-ent-kaur-1,7,15-trione (2), 6-hydroxy-15 beta-acetoxy-3a,20-epoxy-16 beta,17-epoxy-5(6)-ene-ent-kaur-1,7-dione (3), 3a,17-dihydroxy-15(16)-ene-ent-kaur-7-one (4), along with four known compounds 58 were isolated from the leaves of Isodon eriocalyx var. laxiflora. The structures were elucidated by extensive spectroscopic methods (IR, UV, MS and NMR). The cytotoxic activities of these compounds were evaluated by MTT assay. Compound 8 showed moderate inhibitory effects on HL-60, SMMC-7721, MCF-7 and SW-480 cell lines.
学科主题	Chemistry
类目[WOS]	Chemistry, Multidisciplinary
研究领域[WOS]	Chemistry
收录类别	SCI ; IC
资助信息	This project was supported financially by the NSFC-Joint Foundation of Yunnan Province (No. U0832602 to H.-D. Sun), the National Natural Science Foundation of China (No. 81172939 to J.-X. Pu), the Major State Basic Research Development Program of China (Nos. 2009CB522300 and 2009CB940900), the Science and Technology Program of Yunan Province (Nos. 2008IF010 and 2008CD162), and the Major Direction Projection Foundation of CAS Intellectual Innovation Project (No. 2010KIBA05 to J.-X. Pu).
语种	英语
WOS记录号	WOS:000305389200005
公开日期	2014-04-02
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/17608]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Kunming 650201, Yunan, Peoples R China
推荐引用方式 GB/T 7714	Wang Weiguang,Wu Haiyan,Du Xue,et al. ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora[J]. CHINESE JOURNAL OF CHEMISTRY,2012,30(6):1226-1230.
APA	Wang Weiguang.,Wu Haiyan.,Du Xue.,Yan Juming.,Li Yan.,...&Sun Handong.(2012).ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora.CHINESE JOURNAL OF CHEMISTRY,30(6),1226-1230.
MLA	Wang Weiguang,et al."ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora".CHINESE JOURNAL OF CHEMISTRY 30.6(2012):1226-1230.