New steroids and sesquiterpene from Turraea pubescens

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	New steroids and sesquiterpene from Turraea pubescens
	Yuan, Chun-Mao 1,2; Tang, Gui-Hua2 ; Wang, Xiao-Ying 2; Zhang, Yu2 ; Cao, Ming-Ming 2; Li, Xiao-Hui 2; Li, Yan2 ; Li, Shun-Lin 2; Di, Ying-Tong2 ; He, Hong-Ping 2
刊名	FITOTERAPIA
	2013-10-01
卷号	90 页码:119-125
关键词	Turraea pubescens Meliaceae Steroids Sesquiterpene Anti-inflammatory
ISSN号	0367-326X
通讯作者	He,HP (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.,hehongping@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn ; huimhua@163.com
英文摘要	Four new compounds, including three new steroids (1-3) and one new sesquiterpene (6), and two new natural products (4-5), as well as three known steroids (7-9) were isolated from the twigs of Turraea pubescens. Compounds 3-5 are C-22 steroids isolated from the Meliaceae family for the first time. Their structures were elucidated by extensive NMR and MS analyses. Compound 1 exhibited inhibitory activity against lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264.7 cells with an IC50 value of 11.5 mu M. (C) 2013 Elsevier B.V. All rights reserved.
学科主题	Pharmacology & Pharmacy
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]	Pharmacology & Pharmacy
关键词[WOS]	LIMONOIDS ; FLORIBUNDA ; SKELETON
收录类别	SCI
资助信息	National Basic Research Program of China (973 Program) [2009CB522300, 2009CB940900];National Natural Science Funding of China [31170332];Young Academic and Technical Leader Raising Foundation of Yunnan Province [2010CI047]
语种	英语
WOS记录号	WOS:000326427600016
公开日期	2014-01-13
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/17416]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
推荐引用方式 GB/T 7714	Yuan, Chun-Mao,Tang, Gui-Hua,Wang, Xiao-Ying,et al. New steroids and sesquiterpene from Turraea pubescens[J]. FITOTERAPIA,2013,90:119-125.
APA	Yuan, Chun-Mao.,Tang, Gui-Hua.,Wang, Xiao-Ying.,Zhang, Yu.,Cao, Ming-Ming.,...&Hua, Hui-Ming.(2013).New steroids and sesquiterpene from Turraea pubescens.FITOTERAPIA,90,119-125.
MLA	Yuan, Chun-Mao,et al."New steroids and sesquiterpene from Turraea pubescens".FITOTERAPIA 90(2013):119-125.