A novel continuous re-extraction procedure of penicillin G by a micro-extractor based on ceramic membrane

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	A novel continuous re-extraction procedure of penicillin G by a micro-extractor based on ceramic membrane
	Wu, Yong 1,2; Li, Wangliang 2,3; Gao, Hongshuai 1,2; Li, Qiang 2,3; Li, Yuguang 1,2; Wang, Kang 1,2; Mahmood, Iram 1,2; Liu, Huizhou 1
刊名	JOURNAL OF MEMBRANE SCIENCE
	2010-02-01
卷号	347 期号:1-2 页码:17-25
关键词	Penicillin G Micro-extraction Liquid droplets Re-extraction efficiency Degradation Modeling
ISSN号	0376-7388
通讯作者	Liu, H
英文摘要	A ceramic membrane micro-extractor (CME), employed for continuous re-extraction of penicillin G (PEN G), was studied systematically. The droplet size was investigated in the re-extraction process. Re-extraction efficiency (RE) and degradation rate of PEN G were extensively examined by superficial Reynolds number (Re(h)), phase ratio (R), initial PEN G concentration and membrane pore size. To further understand and quantitatively analyze the re-extraction behavior, resistance-in-series (RIS) model was developed to predict the re-extraction efficiency at steady-state conditions. First of all, a three-parameter correlation was defined for quantitative description of droplet size. The main factors affecting the re-extraction efficiency of PEN G were superficial Reynolds number and phase ratio. The re-extraction efficiency of PEN G reached 99% or above at Re(h) > 934 and R > 0.08. Meanwhile, the degradation rate of PEN G (D) decreased to 0.5% when Re(h) was 934. Compared with the re-extraction performance of the batch extractor, less residence time was needed and the degradation rate decreased 50%. The theoretical re-extraction efficiency (BET) was in good agreement with the experimental data. (C) 2009 Elsevier B.V. All rights reserved.
WOS标题词	Science & Technology ; Technology ; Physical Sciences
类目[WOS]	Engineering, Chemical ; Polymer Science
研究领域[WOS]	Engineering ; Polymer Science
关键词[WOS]	CONTINUOUS REACTIVE EXTRACTION ; EMULSION LIQUID-MEMBRANE ; MASS-TRANSFER ; DISTRIBUTION COEFFICIENTS ; INTERFACIAL-TENSION ; HOLLOW-FIBER ; KARR COLUMN ; EMULSIFICATION ; SYSTEMS ; FLOW
收录类别	SCI
语种	英语
WOS记录号	WOS:000273662200003
公开日期	2013-11-27
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.ipe.ac.cn/handle/122111/6219]
专题	过程工程研究所_湿法冶金清洁生产技术国家工程实验室
作者单位	1.Chinese Acad Sci, Inst Proc Engn, Key Lab Green Proc & Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Wu, Yong,Li, Wangliang,Gao, Hongshuai,et al. A novel continuous re-extraction procedure of penicillin G by a micro-extractor based on ceramic membrane[J]. JOURNAL OF MEMBRANE SCIENCE,2010,347(1-2):17-25.
APA	Wu, Yong.,Li, Wangliang.,Gao, Hongshuai.,Li, Qiang.,Li, Yuguang.,...&Liu, Huizhou.(2010).A novel continuous re-extraction procedure of penicillin G by a micro-extractor based on ceramic membrane.JOURNAL OF MEMBRANE SCIENCE,347(1-2),17-25.
MLA	Wu, Yong,et al."A novel continuous re-extraction procedure of penicillin G by a micro-extractor based on ceramic membrane".JOURNAL OF MEMBRANE SCIENCE 347.1-2(2010):17-25.