Chromosome-level genome assembly of hadal snailfish reveals mechanisms of deep-sea adaptation in vertebrates

doi:10.7554/eLife.87198

CORC > 深海科学与工程研究所 > 中国科学院深海科学与工程研究所 > 深海科学研究部 > 深海生物学研究室 > 深海生物蛋白质组学及分子生物学研究组

	Chromosome-level genome assembly of hadal snailfish reveals mechanisms of deep-sea adaptation in vertebrates
	Xu, Wenjie 3; Zhu, Chenglong 3; Gao, Xueli 3; Wu, Baosheng 3; Xu, Han 2; Hu, Mingliang 3; Zeng, Honghui 1; Gan, Xiaoni 1; Feng, Chenguang 3; Zheng, Jiangmin 3
刊名	ELIFE
	2023-12-22
卷号	12 页码:51
关键词	Pseudoliparis swirei muscle brain Liparis tanakae Other
ISSN号	2050-084X
DOI	10.7554/eLife.87198
英文摘要	As the deepest vertebrate in the ocean, the hadal snailfish (Pseudoliparis swirei), which lives at a depth of 6,000-8,000 m, is a representative case for studying adaptation to extreme environments. Despite some preliminary studies on this species in recent years, including their loss of pigmentation, visual and skeletal calcification genes, and the role of trimethylamine N-oxide in adaptation to high-hydrostatic pressure, it is still unknown how they evolved and why they are among the few vertebrate species that have successfully adapted to the deep-sea environment. Using genomic data from different trenches, we found that the hadal snailfish may have entered and fully adapted to such extreme environments only in the last few million years. Meanwhile, phylogenetic relationships show that they spread into different trenches in the Pacific Ocean within a million years. Comparative genomic analysis has also revealed that the genes associated with perception, circadian rhythms, and metabolism have been extensively modified in the hadal snailfish to adapt to its unique environment. More importantly, the tandem duplication of a gene encoding ferritin significantly increased their tolerance to reactive oxygen species, which may be one of the important factors in their adaptation to high-hydrostatic pressure.
资助项目	National Key Research and Development Program of China ; National Natural Science Foundation of China ; The 1000 Talent Project Shaanxi Province ; Fundamental Research Funds of Northwestern Polytechnic University ; Strategic Priority Research Program of Chinese Academy of Sciences
WOS关键词	HIGH HYDROSTATIC-PRESSURE ; PHYLOGENETIC ANALYSIS ; NA+/K+-ATPASE ; PROTEIN ; ZEBRAFISH ; ALIGNMENT ; INSIGHTS ; SYSTEM ; MEMBRANE ; FLUIDITY
WOS研究方向	Life Sciences & Biomedicine - Other Topics
语种	英语
出版者	eLIFE SCIENCES PUBL LTD
WOS记录号	WOS:001129824200001
资助机构	National Key Research and Development Program of China ; National Natural Science Foundation of China ; The 1000 Talent Project Shaanxi Province ; Fundamental Research Funds of Northwestern Polytechnic University ; Strategic Priority Research Program of Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.idsse.ac.cn/handle/183446/10854]
专题	深海科学研究部_深海生物学研究室_深海生物蛋白质组学及分子生物学研究组
通讯作者	He, Shunping; Wang, Kun
作者单位	1.Chinese Acad Sci, Key Lab Aquat Biodivers & Conservat, Inst Hydrobiol, Wuhan, Peoples R China 2.Chinese Acad Sci, Inst Deep Sea Sci & Engn, Sanya, Peoples R China 3.Northwestern Polytech Univ, Sch Ecol & Environm, Xian, Peoples R China
推荐引用方式 GB/T 7714	Xu, Wenjie,Zhu, Chenglong,Gao, Xueli,et al. Chromosome-level genome assembly of hadal snailfish reveals mechanisms of deep-sea adaptation in vertebrates[J]. ELIFE,2023,12:51.
APA	Xu, Wenjie.,Zhu, Chenglong.,Gao, Xueli.,Wu, Baosheng.,Xu, Han.,...&Wang, Kun.(2023).Chromosome-level genome assembly of hadal snailfish reveals mechanisms of deep-sea adaptation in vertebrates.ELIFE,12,51.
MLA	Xu, Wenjie,et al."Chromosome-level genome assembly of hadal snailfish reveals mechanisms of deep-sea adaptation in vertebrates".ELIFE 12(2023):51.