Dual-Mode Undistorted Visual Fluorescent Sensing Strategy through Manipulating the Coffee-Ring Effect on Microfluidic Paper-Based Chip

doi:10.1021/acs.analchem.3c00947

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	Dual-Mode Undistorted Visual Fluorescent Sensing Strategy through Manipulating the Coffee-Ring Effect on Microfluidic Paper-Based Chip
	Qi, Ji 3,4; Li, Bowei 4; Lin, Dong 4; Du, Zhiqiang 4; Fu, Longwen 4; Wang, Xiaoyan 2; Zhang, Zhiyang 4; Luo, Liqiang 1; Chen, Lingxin 2,4
刊名	ANALYTICAL CHEMISTRY
	2023-07-07
卷号	95 期号:28 页码:10486-10491
ISSN号	0003-2700
DOI	10.1021/acs.analchem.3c00947
通讯作者	Li, Bowei(bwli@yic.ac.cn) ; Luo, Liqiang(luck@shu.edu.cn) ; Chen, Lingxin(lxchen@yic.ac.cn)
英文摘要	To overcome the insufficient sensitivity due to distortionof thefluorescent images by mobile devices, we first developed a novel dual-modestrategy for undistorted visual fluorescent sensing on & mu;PADby technically manipulating the coffee-ring effect of the fluid sample.Based on the manipulating coffee-ring effect, we divided the horizontaldirection of the resulting fluorescence image into 600 pixels andobtained more accurate quantitative information to avoid image distortion.The bovine serum albumin-stabilized gold nanoclusters-copperion complex was used as the fluorescent probe, combined with a smallimaging box and a smartphone, to achieve a rapid testing of histidinein human urine. The output image was analyzed in dual mode: RGB numericalanalysis in pixel units and the direct measurement of the fluorescentstrips length (limit of detection (LOD) is 0.021 and 0.5 mM, respectively),and improved antidistortion for visual fluorescent sensing. This strategycan overcome the distortion of a smartphone-visualized fluorescentimage and shows great potential for rapid and convenient analysis.
WOS关键词	ASSAY
WOS研究方向	Chemistry
语种	英语
WOS记录号	WOS:001024816600001
资助机构	National Natural Science Foundation of China ; Shandong Provincial Natural Science Foundation Key Project ; Open Fund Project of Key Laboratory of Ocean Observation Technology
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/33363]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
通讯作者	Li, Bowei; Luo, Liqiang; Chen, Lingxin
作者单位	1.Shanghai Univ, Coll Sci, Shanghai 200444, Peoples R China 2.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China 3.MNR, Key Lab Ocean Observat Technol, Tianjin 300110, Peoples R China 4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
推荐引用方式 GB/T 7714	Qi, Ji,Li, Bowei,Lin, Dong,et al. Dual-Mode Undistorted Visual Fluorescent Sensing Strategy through Manipulating the Coffee-Ring Effect on Microfluidic Paper-Based Chip[J]. ANALYTICAL CHEMISTRY,2023,95(28):10486-10491.
APA	Qi, Ji.,Li, Bowei.,Lin, Dong.,Du, Zhiqiang.,Fu, Longwen.,...&Chen, Lingxin.(2023).Dual-Mode Undistorted Visual Fluorescent Sensing Strategy through Manipulating the Coffee-Ring Effect on Microfluidic Paper-Based Chip.ANALYTICAL CHEMISTRY,95(28),10486-10491.
MLA	Qi, Ji,et al."Dual-Mode Undistorted Visual Fluorescent Sensing Strategy through Manipulating the Coffee-Ring Effect on Microfluidic Paper-Based Chip".ANALYTICAL CHEMISTRY 95.28(2023):10486-10491.