Natural brain state change with E/I balance shifting toward inhibition is associated with vigilance impairment

doi:10.1016/j.isci.2023.107963

CORC > 自动化研究所 > 中国科学院自动化研究所 > 脑图谱与类脑智能实验室

	Natural brain state change with E/I balance shifting toward inhibition is associated with vigilance impairment
	Yang, Binghao 3,4; Zhang, Haoran 3,4; Jiang, Tianzi 1,2,4; Yu, Shan 2,3,4
刊名	ISCIENCE
	2023-10-20
卷号	26 期号:10 页码:17
DOI	10.1016/j.isci.2023.107963
通讯作者	Yu, Shan(shan.yu@nlpr.ia.ac.cn)
英文摘要	The delicate balance between cortical excitation and inhibition (E/I) plays a pivotal role in brain state changes. While previous studies have associated cortical hyperexcitability with brain state changes induced by sleep deprivation, whether cortical hypoexcitability is also linked to brain state changes and, if so, how it could affect cognitive performance remain unknown. Here, we address these questions by examining the brain state change occurring after meals, i.e., postprandial somnolence, and comparing it with that induced by sleep deprivation. By analyzing features representing network excitability based on electroencephalogram (EEG) signals, we confirmed cortical hyperexcitability under sleep deprivation but revealed hypoexcitability under postprandial somnolence. In addition, we found that both sleep deprivation and postprandial somnolence adversely affected the level of vigilance. These results indicate that cortical E/I balance toward inhibition is associated with brain state changes, and deviation from the balanced state, regardless of its direction, could impair cognitive performance.
资助项目	International Partnership Program of the Chinese Academy of Sciences (CAS)[173211KYSB20200021] ; STI 2030-Major Project[2021ZD0200402] ; STI 2030-Major Project[2021ZD0200200]
WOS关键词	RANGE TEMPORAL CORRELATIONS ; THETA-BURST STIMULATION ; NEURONAL AVALANCHES ; CORTICAL NETWORKS ; SLEEP ; DYNAMICS ; EXCITATION ; WAKEFULNESS ; INCREASES ; MEMORY
WOS研究方向	Science & Technology - Other Topics
语种	英语
出版者	CELL PRESS
WOS记录号	WOS:001089060200001
资助机构	International Partnership Program of the Chinese Academy of Sciences (CAS) ; STI 2030-Major Project
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/54331]
专题	脑图谱与类脑智能实验室
通讯作者	Yu, Shan
作者单位	1.Zhejiang Lab, Res Ctr Augmented Intelligence, Hangzhou 311121, Peoples R China 2.Univ Chinese Acad Sci, Sch Artificial Intelligence, Beijing 101408, Peoples R China 3.Univ Chinese Acad Sci, Sch Future Technol, Beijing 101408, Peoples R China 4.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, Lab Brain Atlas & Brain inspired Intelligence, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Yang, Binghao,Zhang, Haoran,Jiang, Tianzi,et al. Natural brain state change with E/I balance shifting toward inhibition is associated with vigilance impairment[J]. ISCIENCE,2023,26(10):17.
APA	Yang, Binghao,Zhang, Haoran,Jiang, Tianzi,&Yu, Shan.(2023).Natural brain state change with E/I balance shifting toward inhibition is associated with vigilance impairment.ISCIENCE,26(10),17.
MLA	Yang, Binghao,et al."Natural brain state change with E/I balance shifting toward inhibition is associated with vigilance impairment".ISCIENCE 26.10(2023):17.