Identification, classification and expression analysis of the Ras superfamily genes in the Pacific white shrimp, Litopenaeus vannamei | |
Si, Shuqing1,2,3; Zhang, Xiaojun1,2,3,4,5; Yuan, Jianbo2,3,4,5; Zhang, Xiaoxi2,3,4,5; Yu, Yang2,3,4,5; Yang, Song1; Li, Fuhua2,3,4,5 | |
刊名 | FRONTIERS IN MARINE SCIENCE |
2023-01-23 | |
卷号 | 10页码:17 |
关键词 | Ras superfamily GTPase proteins Litopenaeus vannamei gene structure and function gene expression immunity growth |
DOI | 10.3389/fmars.2023.1063857 |
通讯作者 | Zhang, Xiaojun(xjzhang@qdio.ac.cn) ; Yang, Song(yangsong1209@163.com) |
英文摘要 | The Ras superfamily of small guanosine triphosphatases (GTPases) are a large group of small GTP-binding proteins, which play crucial roles in basic cellular processes in all eukaryotes. In this study, by analyzing the gene structure, temporal and spatial expression patterns, a total of 108 Ras superfamily genes were identified in the genome of the Pacific white shrimp Litopenaeus vannamei. We found these genes included not only the classical Ras GTPase superfamily members, but also some unconventional and novel Ras GTPase proteins, which have unknown functions and unique expression patterns. All Ras superfamily genes of L. vannamei were highly conserved within the core G domain and closely related in phylogeny, but they might have two different evolutionary origins. In addition, different Ras GTPase genes exhibited distinct expression patterns in different tissues, development/molting stages and WSSV infection samples of L. vannamei, suggesting that they may have a high functional specialization, and play important roles in regulating the biological processes of cell differentiation, growth and development, immune response, etc. This study provides important clues for the structure, classification, evolution and function of Ras superfamily in shrimp. |
资助项目 | Strategic Priority Research Program of the Chinese Academy of Sciences[XDA24030105] ; National Key R&D Program of China[2018YFD0900103] ; National Key R&D Program of China[2022YFF1000304] ; National Natural Sciences Foundation of China[31972782] ; National Natural Sciences Foundation of China[32273102] |
WOS关键词 | SMALL GTPASES ; NEURONAL DIFFERENTIATION ; ACTIVATING PROTEINS ; CRYSTAL-STRUCTURE ; RHO-GTPASES ; FAMILY ; TRANSPORT ; PHAGOCYTOSIS ; COMPLEX ; MEMBER |
WOS研究方向 | Environmental Sciences & Ecology ; Marine & Freshwater Biology |
语种 | 英语 |
出版者 | FRONTIERS MEDIA SA |
WOS记录号 | WOS:000924629800001 |
内容类型 | 期刊论文 |
源URL | [http://ir.qdio.ac.cn/handle/337002/183415] |
专题 | 海洋研究所_实验海洋生物学重点实验室 |
通讯作者 | Zhang, Xiaojun; Yang, Song |
作者单位 | 1.Qingdao Agr Univ, Sch Life & Sci, Qingdao, Peoples R China 2.Inst Oceanol, Chinese Acad Sci, Qingdao, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Shandong Prov Key Lab Expt Marine Biol, Qingdao, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 5.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China |
推荐引用方式 GB/T 7714 | Si, Shuqing,Zhang, Xiaojun,Yuan, Jianbo,et al. Identification, classification and expression analysis of the Ras superfamily genes in the Pacific white shrimp, Litopenaeus vannamei[J]. FRONTIERS IN MARINE SCIENCE,2023,10:17. |
APA | Si, Shuqing.,Zhang, Xiaojun.,Yuan, Jianbo.,Zhang, Xiaoxi.,Yu, Yang.,...&Li, Fuhua.(2023).Identification, classification and expression analysis of the Ras superfamily genes in the Pacific white shrimp, Litopenaeus vannamei.FRONTIERS IN MARINE SCIENCE,10,17. |
MLA | Si, Shuqing,et al."Identification, classification and expression analysis of the Ras superfamily genes in the Pacific white shrimp, Litopenaeus vannamei".FRONTIERS IN MARINE SCIENCE 10(2023):17. |
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