The initial application of conch-shell hydroxyapatite and HACC as functional filler in PMMA bone cement

doi:10.1080/00914037.2023.2243367

CORC > 海洋研究所 > 中国科学院海洋研究所 > 实验海洋生物学重点实验室

	The initial application of conch-shell hydroxyapatite and HACC as functional filler in PMMA bone cement
	Tian, Luqi 2,3,4; Xing, Ronge 1,2,3,5,6; Yang, Haoyue 2,3; Liu, Song 2,3,5; Yu, Huahua 2,3,5; Li, Pengcheng 2,3,5
刊名	INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
	2023-08-05
页码	10
关键词	Conch shell HACC hydroxyapatite PMMA bone cement >
ISSN号	0091-4037
DOI	10.1080/00914037.2023.2243367
通讯作者	Xing, Ronge(xingronge@qdio.ac.cn)
英文摘要	In this study, we acquired conch-shell Hydroxyapatite (cHA)with a mean size of 99.41 nm using a microwave-assisted method, and hydroxypropyl trimethyl ammonium chloride chitosan (HACC) with a molecular weight of 41 kDa was synthesized from deacetylated chitosan. These two additives were added to plain PMMA bone cement, improving its biological activity. It was shown that the addition of cHA and HACC balanced the mechanical performance and porosity of the implant, improving its biocompatibility with mouse pre-osteoblasts (MC3T3-E1). A composite cement with 30 wt% cHA and 0.5 wt% HACC significantly enhanced mineralization efficiency, protein adsorption, and alkaline phosphatase (ALP) activity.
资助项目	Fujian science and technology planning project-STS program[2021T3013] ; Key deployment projects of the Marine Science Research Center of Chinese Academy of Sciences[COMS2020J04]
WOS关键词	SCAFFOLDS ; BIOACTIVITY
WOS研究方向	Materials Science ; Polymer Science
语种	英语
出版者	TAYLOR & FRANCIS AS
WOS记录号	WOS:001041713200001
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/182640]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Xing, Ronge
作者单位	1.Chinese Acad Sci, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Qingdao, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, Shandong Prov Key Lab Expt Marine Biol, Qingdao, Peoples R China 4.Univ Chinese Acad Sci, Beijing, Peoples R China 5.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Drugs & Bioprod, Qingdao, Peoples R China 6.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Tian, Luqi,Xing, Ronge,Yang, Haoyue,et al. The initial application of conch-shell hydroxyapatite and HACC as functional filler in PMMA bone cement[J]. INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS,2023:10.
APA	Tian, Luqi,Xing, Ronge,Yang, Haoyue,Liu, Song,Yu, Huahua,&Li, Pengcheng.(2023).The initial application of conch-shell hydroxyapatite and HACC as functional filler in PMMA bone cement.INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS,10.
MLA	Tian, Luqi,et al."The initial application of conch-shell hydroxyapatite and HACC as functional filler in PMMA bone cement".INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS (2023):10.