Activity labelled molecular networking fuels the antioxidation active molecules profile of Ginger

	Activity labelled molecular networking fuels the antioxidation active molecules profile of Ginger
	Wang, Qiqi; Chen, Tao; La, Mencuo; Song, Zhibo; Gao, Mengze; Yang, Tingqin; Li, Yulin; He, Liangliang; Zou, Denglang
刊名	FOOD CHEMISTRY
	2023
卷号	424
英文摘要	Ginger has been used as consumed food spice and folk medicine in daily life for thousands of years in various regions of the world. Considerable antioxidation is one of the major activities for Ginger to exhibit healthpromoting effects. In this study, a bioinformatic workflow was developed to generate activity labelled molecular networking (ALMN) to fuel the antioxidation active molecules profile of Ginger. In ALMN, antioxidation activity data, which was defined as correlation (r and p value) between the relative abundance of a molecule in fractions and the activity level of each fraction, was labelled to feature-based molecular network to profile out antioxidation active molecules visually. Fragmentation tree was further computed as a complementary way to conduct high confidence structure annotations of antioxidation active molecules. Consequently, 48 molecules were prioritized as antioxidation active molecules from 11,720 metabolite molecules of Ginger in a systematical way.
内容类型	期刊论文
源URL	[http://210.75.249.4/handle/363003/61641]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Wang, Qiqi,Chen, Tao,La, Mencuo,et al. Activity labelled molecular networking fuels the antioxidation active molecules profile of Ginger[J]. FOOD CHEMISTRY,2023,424.
APA	Wang, Qiqi.,Chen, Tao.,La, Mencuo.,Song, Zhibo.,Gao, Mengze.,...&Zou, Denglang.(2023).Activity labelled molecular networking fuels the antioxidation active molecules profile of Ginger.FOOD CHEMISTRY,424.
MLA	Wang, Qiqi,et al."Activity labelled molecular networking fuels the antioxidation active molecules profile of Ginger".FOOD CHEMISTRY 424(2023).