Dynamic semiparametric transformation models for recurrent event data with a terminal event
Jin, Jin1; Song, Xinyuan2; Sun, Liuquan3,4
刊名STATISTICS IN MEDICINE
2022-09-19
页码16
关键词dynamic regression marginal modeling recurrent events terminal event time-varying coefficients transformation models
ISSN号0277-6715
DOI10.1002/sim.9577
英文摘要Recurrent event data with a terminal event commonly arise in many longitudinal follow-up studies. This article proposes a class of dynamic semiparametric transformation models for the marginal mean functions of the recurrent events with a terminal event, where some covariate effects may be time-varying. An estimation procedure is developed for the model parameters, and the asymptotic properties of the resulting estimators are established. In addition, relevant significance tests are suggested for examining whether or not covariate effects vary with time, and a model checking procedure is presented for assessing the adequacy of the proposed models. The finite sample performance of the proposed estimators is examined through simulation studies, and an application to a medical cost study of chronic heart failure patients is provided.
资助项目National Natural Science Foundation of China[12171463] ; National Natural Science Foundation of China[11771431] ; National Natural Science Foundation of China[11690015] ; Research Grant Council of the Hong Kong Special Administrative Region[14302220]
WOS研究方向Mathematical & Computational Biology ; Public, Environmental & Occupational Health ; Medical Informatics ; Research & Experimental Medicine ; Mathematics
语种英语
出版者WILEY
WOS记录号WOS:000857871700001
内容类型期刊论文
源URL[http://ir.amss.ac.cn/handle/2S8OKBNM/61007]  
专题中国科学院数学与系统科学研究院
通讯作者Sun, Liuquan
作者单位1.Univ Sci & Technol Beijing, Sch Math & Phys, Beijing, Peoples R China
2.Chinese Univ Hong Kong, Dept Stat, Hong Kong, Peoples R China
3.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing, Peoples R China
4.Univ Chinese Acad Sci, Sch Math Sci, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Jin, Jin,Song, Xinyuan,Sun, Liuquan. Dynamic semiparametric transformation models for recurrent event data with a terminal event[J]. STATISTICS IN MEDICINE,2022:16.
APA Jin, Jin,Song, Xinyuan,&Sun, Liuquan.(2022).Dynamic semiparametric transformation models for recurrent event data with a terminal event.STATISTICS IN MEDICINE,16.
MLA Jin, Jin,et al."Dynamic semiparametric transformation models for recurrent event data with a terminal event".STATISTICS IN MEDICINE (2022):16.
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