The psychological impact of esophageal cancer screening on anxiety and depression in China

doi:10.3389/fpsyt.2022.933678

	The psychological impact of esophageal cancer screening on anxiety and depression in China
	Zhu, Juan 1,4; Ma, Shanrui 4; Chen, Ru 4; Liu, Zhaorui 2; Liu, Zhengkui 3; Wei, Wenqiang 4
刊名	FRONTIERS IN PSYCHIATRY
	2022-10-20
卷号	13
关键词	esophageal cancer screening endoscopy anxiety depression psychological impact high-risk regions
ISSN号	1664-0640
DOI	10.3389/fpsyt.2022.933678
通讯作者	Wei, Wenqiang(weiwq@cicams.ac.cn)
英文摘要	ObjectiveThe psychological impact of screening is unclear and has been ignored. This study aimed to evaluate the psychological impact of esophageal cancer (EC) screening on anxiety and depression in China. Materials and methodsA multicenter, population-based study in five high-risk regions of EC was conducted from 2019 to 2020. Residents were recruited and underwent endoscopic screening and then were diagnosed with normal, esophagitis, low-grade intraepithelial neoplasia (LGIN), high-grade intraepithelial neoplasia (HGIN) and EC. Subjects who did not participate in the screening were referred to as the control group. We surveyed their anxiety and depression levels at baseline and after endoscopy and informed them of different pathological results to evaluate the psychological impact of the screening process. ResultsA total of 2,337 subjects completed all surveys in the screening process (normal: 355, esophagitis: 1,713, LGIN: 213, HGIN: 43 and EC: 13), with 63 controls. The levels of anxiety and depression of screeners were significantly higher than those of controls (P < 0.001). The fluctuation of anxiety and depression showed a "V" pattern in the screening process. The prevalence of anxiety symptoms at baseline, after endoscopy and after knowing the pathological results was 5.6, 0.3, and 3.2%, respectively (P < 0.001), and the corresponding prevalence of depression was 3.6, 0.2, and 2.1%, respectively (P < 0.001). With the aggravation of pathological results, the levels of anxiety and depression increased significantly (P < 0.001), especially in patients informed of HGIN (16.3 and 9.3%) and EC (23.1 and 30.8%). ConclusionParticipation in endoscopic screening may bring short-term adverse psychological effects, especially at baseline and knowing the pathological results. More attention should be given to participants waiting for endoscopic screening. The method of informing the screening results of HGIN and EC should be improved. Further precise screening is needed to concentrate on high-risk groups to reduce the psychological impact of screening.
WOS关键词	BREAST-CANCER ; DIAGNOSIS ; PREVALENCE ; DISORDERS ; MORTALITY ; EFFICACY ; OUTCOMES ; STRESS ; DESIGN ; RISK
WOS研究方向	Psychiatry
语种	英语
出版者	FRONTIERS MEDIA SA
WOS记录号	WOS:000879035400001
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/129923]
专题	中国科学院合肥物质科学研究院
通讯作者	Wei, Wenqiang
作者单位	1.Chinese Acad Sci, Dept Canc Prevent, Canc Hosp, Univ Chinese Acad Sci,Zhejiang Canc Hosp,Inst Canc, Hangzhou, Peoples R China 2.Peking Univ, Inst Mental Hlth, Key Lab Mental Hlth, Minist Hlth, Beijing, Peoples R China 3.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing, Peoples R China 4.Chinese Acad Med Sci & Peking Union Med Coll, Natl Cent Canc Registry, Natl Canc Ctr, Natl Clin Res Ctr Canc,Canc Hosp, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Zhu, Juan,Ma, Shanrui,Chen, Ru,et al. The psychological impact of esophageal cancer screening on anxiety and depression in China[J]. FRONTIERS IN PSYCHIATRY,2022,13.
APA	Zhu, Juan,Ma, Shanrui,Chen, Ru,Liu, Zhaorui,Liu, Zhengkui,&Wei, Wenqiang.(2022).The psychological impact of esophageal cancer screening on anxiety and depression in China.FRONTIERS IN PSYCHIATRY,13.
MLA	Zhu, Juan,et al."The psychological impact of esophageal cancer screening on anxiety and depression in China".FRONTIERS IN PSYCHIATRY 13(2022).