Green synthesis of ultrasmall selenium nanoparticles (SeNPs) using Hericium erinaceus polysaccharide (HEP) as nanozymes for efficient intracellular antioxidation

doi:10.1016/j.matlet.2022.132079

	Green synthesis of ultrasmall selenium nanoparticles (SeNPs) using Hericium erinaceus polysaccharide (HEP) as nanozymes for efficient intracellular antioxidation
	He, Huaqi 2,3; Liu, Chao 1,3; Shao, Changsheng 1,3; Wu, Yahui 1,3; Huang, Qing 1,2,3
刊名	MATERIALS LETTERS
	2022-06-15
卷号	317
关键词	Selenium Nanoparticles (NPs) Nanozymes Hericium erinaceus polysaccharide (HEP) Biomaterials Antioxidant
ISSN号	0167-577X
DOI	10.1016/j.matlet.2022.132079
通讯作者	Huang, Qing(huangq@ipp.ac.cn)
英文摘要	As one of essential trace elements for the human body, selenium plays an important role in antioxidation by scavenging free radicals. Especially, selenium nanoparticles (SeNPs) nowadays attract increasing attention due to their low toxicity and high biocompatibility. In this work, we introduced a facile method of green synthesis of ultra-small monodisperse SeNPs using Hericium erinaceus polysaccharides (HEP), and investigated the antioxidant property and biocompatibility of the as-prepared SeNPs. Our results showed that the HEP-SeNPs had the excellent antioxidant ability to eliminate reactive oxygen species (ROS) efficiently, and it could act as mimic enzymes or nanozymes such as catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx). The cell experiment confirmed the outstanding cell protection ability against external oxidative stress. Therefore, this work has not only put forward a facile and efficient method of green synthesis of ultra-small selenium nanoparticles with excellent antioxidant capacity and biocompatibility, but also demonstrated the potential application of the HEP-SeNPs as the nanozymes in biological applications such as strong antioxidants.
资助项目	Anhui Provincial Key Research and Development Plan[202004i07020014] ; Research Integration Program of Hefei Institutes of Physical Science, Chinese Academy of Sciences
WOS关键词	SE
WOS研究方向	Materials Science ; Physics
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000810791800003
资助机构	Anhui Provincial Key Research and Development Plan ; Research Integration Program of Hefei Institutes of Physical Science, Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/129582]
专题	中国科学院合肥物质科学研究院
通讯作者	Huang, Qing
作者单位	1.Univ Sci & Technol China, Grad Sch, Sci Isl Branch, Hefei 230026, Peoples R China 2.Anhui Sci & Technol Univ, Coll Agr, Fengyang 233100, Peoples R China 3.Chinese Acad Sci, Inst Intelligent Machines, Inst Intelligent Agr, Hefei Inst Phys Sci, Hefei 230031, Peoples R China
推荐引用方式 GB/T 7714	He, Huaqi,Liu, Chao,Shao, Changsheng,et al. Green synthesis of ultrasmall selenium nanoparticles (SeNPs) using Hericium erinaceus polysaccharide (HEP) as nanozymes for efficient intracellular antioxidation[J]. MATERIALS LETTERS,2022,317.
APA	He, Huaqi,Liu, Chao,Shao, Changsheng,Wu, Yahui,&Huang, Qing.(2022).Green synthesis of ultrasmall selenium nanoparticles (SeNPs) using Hericium erinaceus polysaccharide (HEP) as nanozymes for efficient intracellular antioxidation.MATERIALS LETTERS,317.
MLA	He, Huaqi,et al."Green synthesis of ultrasmall selenium nanoparticles (SeNPs) using Hericium erinaceus polysaccharide (HEP) as nanozymes for efficient intracellular antioxidation".MATERIALS LETTERS 317(2022).