Hypericum perforatum extract therapy for chickens experimentally infected with infectious bursal disease virus and its influence on immunity

	Hypericum perforatum extract therapy for chickens experimentally infected with infectious bursal disease virus and its influence on immunity
	Shang, Ruofeng 1,3; He, Cheng 4; Chen, Jiongran 1,3; Pu, Xiuying 2; Liu, Yu 1,3; Hua, Lanying 1,3; Wang, Ling 1,3; Liang, Jianping 1,3
刊名	CANADIAN JOURNAL OF VETERINARY RESEARCH-REVUE CANADIENNE DE RECHERCHE VETERINAIRE
	2012-07
卷号	76 期号:3 页码:180-185
ISSN号	0830-9000
英文摘要	Hypericum perforatum extract (HPE) has been proved a drug effective to many viral diseases. The purpose of this paper was to investigate the therapeutic efficacy and immuno-enhancement of HPE for chickens which were already challenged with infectious bursal disease virus (IBDV BC-6/85). Chickens infected with IBDV were treated with HPE for 5 consecutive days, the observation of immune organ indexes and pathological changes index, determination of IFN-alpha and detection of IBDV with RT-PCR were employed to assess in vivo whether or not HPE had the certain therapeutic efficacy on infectious bursal disease (IBD), and if HPE was able to improve the immunologic function. The results showed that 1330 and 667.9 mg/kg body weight (BW) per day of HPE had significant therapeutic efficacy and improvement immunologic functions for chickens infected experimentally with IBDV.
资助项目	National Science & Technology Pillar Program[2006BAD31B05]
WOS研究方向	Veterinary Sciences
语种	英语
出版者	CANADIAN VET MED ASSOC
WOS记录号	WOS:000309169900004
状态	已发表
内容类型	期刊论文
源URL	[http://119.78.100.223/handle/2XXMBERH/34893]
专题	生命科学与工程学院
通讯作者	Liang, Jianping
作者单位	1.Chinese Acad Agr Sci, Lanzhou Inst Anim Sci & Vet Pharmaceut Sci, Minist Agr, Key Lab Vet Pharmaceut, Lanzhou 730050, Peoples R China 2.Lanzhou Univ Technol, Lanzhou 730050, Peoples R China 3.Chinese Acad Agr Sci, Lanzhou Inst Anim Sci & Vet Pharmaceut Sci, Key Lab New Anim Drug Project, Lanzhou 730050, Peoples R China 4.China Agr Univ, Coll Vet Med, Beijing 10094, Peoples R China
推荐引用方式 GB/T 7714	Shang, Ruofeng,He, Cheng,Chen, Jiongran,et al. Hypericum perforatum extract therapy for chickens experimentally infected with infectious bursal disease virus and its influence on immunity[J]. CANADIAN JOURNAL OF VETERINARY RESEARCH-REVUE CANADIENNE DE RECHERCHE VETERINAIRE,2012,76(3):180-185.
APA	Shang, Ruofeng.,He, Cheng.,Chen, Jiongran.,Pu, Xiuying.,Liu, Yu.,...&Liang, Jianping.(2012).Hypericum perforatum extract therapy for chickens experimentally infected with infectious bursal disease virus and its influence on immunity.CANADIAN JOURNAL OF VETERINARY RESEARCH-REVUE CANADIENNE DE RECHERCHE VETERINAIRE,76(3),180-185.
MLA	Shang, Ruofeng,et al."Hypericum perforatum extract therapy for chickens experimentally infected with infectious bursal disease virus and its influence on immunity".CANADIAN JOURNAL OF VETERINARY RESEARCH-REVUE CANADIENNE DE RECHERCHE VETERINAIRE 76.3(2012):180-185.