Insights into the Structures, Inhibitors, and Improvement Strategies of Glucose Oxidase

doi:10.3390/ijms23179841

	Insights into the Structures, Inhibitors, and Improvement Strategies of Glucose Oxidase
	Wang, Fan 2; Chen, Xiaona 1,2; Wang, Yonggang 1; Li, Xing 2; Wan, Minglai 1,2; Zhang, Ge 2; Leng, Feifan 1; Zhang, Haibo 2
刊名	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
	2022-09-01
卷号	23 期号:17
关键词	glucose oxidase structures inhibitors yield improvement
DOI	10.3390/ijms23179841
英文摘要	Glucose oxidase, which uses molecular oxygen as an electron acceptor to specifically catalyze the conversion of beta-d-glucose to gluconic acid and hydrogen peroxide (H2O2), has been considered an important enzyme in increasing environmental sustainability and food security. However, achieving the high yield, low price and high activity required for commercial viability remains challenging. In this review, we first present a brief introduction, looking at the sources, characteristics, catalytic process, and applications of glucose oxidase. Then, the predictive structures of glucose oxidase from two different sources are comparatively discussed. We summarize the inhibitors of glucose oxidase. Finally, we highlight how the production of glucose oxidase can be improved by optimizing the culture conditions and microbial metabolic engineering.
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
出版者	MDPI
WOS记录号	WOS:000852508900001
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/159836]
专题	生命科学与工程学院
作者单位	1.Lanzhou Univ Technol, Sch Life Sci & Engn, Lanzhou 730050, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China;
推荐引用方式 GB/T 7714	Wang, Fan,Chen, Xiaona,Wang, Yonggang,et al. Insights into the Structures, Inhibitors, and Improvement Strategies of Glucose Oxidase[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2022,23(17).
APA	Wang, Fan.,Chen, Xiaona.,Wang, Yonggang.,Li, Xing.,Wan, Minglai.,...&Zhang, Haibo.(2022).Insights into the Structures, Inhibitors, and Improvement Strategies of Glucose Oxidase.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,23(17).
MLA	Wang, Fan,et al."Insights into the Structures, Inhibitors, and Improvement Strategies of Glucose Oxidase".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23.17(2022).