Zn(OTf)(2)-catalyzed hydroamination of ynamides with aromatic amines

doi:10.1039/d0ob02603d

	Zn(OTf)(2)-catalyzed hydroamination of ynamides with aromatic amines
	Chen, Zhuo 1,2; Nie, Xiao-Di 1; Sun, Jian-Ting 1; Yang, Ai-Mei 2; Wei, Bang-Guo 1
刊名	ORGANIC & BIOMOLECULAR CHEMISTRY
	2021
卷号	19 期号:11 页码:2492-2501
ISSN号	1477-0520
DOI	10.1039/d0ob02603d
英文摘要	The Zn(OTf)(2)-catalyzed hydroamination of ynamides 2a-2l with aromatic amines 1a-1r was developed. This protocol features broad substrate scope of aromatic amines, good functional group tolerance for ynamides, and excellent regioselectivities. As a result, a variety of substituted amidine compounds 3aa-3oa, 3ab-3al and 3pa-3rk were prepared in moderate to excellent yields and with high regioselectivities.
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000632575900015
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/148309]
专题	生命科学与工程学院
作者单位	1.Fudan Univ, Sch Pharm, Dept Nat Med, 826 Zhangheng Rd, Shanghai 201203, Peoples R China 2.Lanzhou Univ Technol, Sch Life Sci & Engn, Lanzhou 730050, Peoples R China;
推荐引用方式 GB/T 7714	Chen, Zhuo,Nie, Xiao-Di,Sun, Jian-Ting,et al. Zn(OTf)(2)-catalyzed hydroamination of ynamides with aromatic amines[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2021,19(11):2492-2501.
APA	Chen, Zhuo,Nie, Xiao-Di,Sun, Jian-Ting,Yang, Ai-Mei,&Wei, Bang-Guo.(2021).Zn(OTf)(2)-catalyzed hydroamination of ynamides with aromatic amines.ORGANIC & BIOMOLECULAR CHEMISTRY,19(11),2492-2501.
MLA	Chen, Zhuo,et al."Zn(OTf)(2)-catalyzed hydroamination of ynamides with aromatic amines".ORGANIC & BIOMOLECULAR CHEMISTRY 19.11(2021):2492-2501.