Robustness, Death of Spiral Wave in the Network of Neurons under Partial Ion Channel Block

doi:10.1088/0253-6102/59/2/16

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	Robustness, Death of Spiral Wave in the Network of Neurons under Partial Ion Channel Block
	Ma Jun; Huang Long; Wang Chun-Ni; Pu Zhong-Sheng
刊名	COMMUNICATIONS IN THEORETICAL PHYSICS
	2013-02
卷号	59 期号:2 页码:233-242
关键词	spiral wave channel block network of neuron
ISSN号	0253-6102
DOI	10.1088/0253-6102/59/2/16
英文摘要	The development of spiral wave in a two-dimensional square array due to partial ion channel block (Potassium, Sodium) is investigated, the dynamics of the node is described by Hodgkin-Huxley neuron and these neurons are coupled with nearest neighbor connection. The parameter ratio x(Na) (and x(K)), which defines the ratio of working ion channel number of sodium (potassium) to the total ion channel number of sodium (and potassium), is used to measure the shift conductance induced by channel block. The distribution of statistical variable R in the two-parameter phase space (parameter ratio vs. poisoning area) is extensively calculated to mark the parameter region for transition of spiral wave induced by partial ion channel block, the area with smaller factors of synchronization R is associated the parameter region that spiral wave keeps alive and robust to the channel poisoning. Spiral wave keeps alive when the poisoned area (potassium or sodium) and degree of intoxication are small, distinct transition (death, several spiral waves coexist or multi-arm spiral wave emergence) occurs under moderate ratio x(Na) (and x(K)) when the size of blocked area exceeds certain thresholds. Breakup of spiral wave occurs and multi-arm of spiral waves are observed when the channel noise is considered.
资助项目	National Natural Science Foundation of China[11265008]
WOS研究方向	Physics
语种	英语
出版者	IOP PUBLISHING LTD
WOS记录号	WOS:000315520300016
状态	已发表
内容类型	期刊论文
源URL	[http://119.78.100.223/handle/2XXMBERH/34752]
专题	理学院
通讯作者	Ma Jun
作者单位	Lanzhou Univ Technol, Dept Phys, Lanzhou 730050, Peoples R China
推荐引用方式 GB/T 7714	Ma Jun,Huang Long,Wang Chun-Ni,et al. Robustness, Death of Spiral Wave in the Network of Neurons under Partial Ion Channel Block[J]. COMMUNICATIONS IN THEORETICAL PHYSICS,2013,59(2):233-242.
APA	Ma Jun,Huang Long,Wang Chun-Ni,&Pu Zhong-Sheng.(2013).Robustness, Death of Spiral Wave in the Network of Neurons under Partial Ion Channel Block.COMMUNICATIONS IN THEORETICAL PHYSICS,59(2),233-242.
MLA	Ma Jun,et al."Robustness, Death of Spiral Wave in the Network of Neurons under Partial Ion Channel Block".COMMUNICATIONS IN THEORETICAL PHYSICS 59.2(2013):233-242.