Effect of inhomogeneous distribution of ion channels on collective electric activities of neurons in a ring network

doi:10.7498/aps.62.240507

CORC > 兰州理工大学 > 兰州理工大学 > 理学院

	Effect of inhomogeneous distribution of ion channels on collective electric activities of neurons in a ring network
	Wu Xin-Yi; Ma Jun; Xie Zhen-Bo
刊名	ACTA PHYSICA SINICA
	2013-12
卷号	62 期号:24 页码:240507
关键词	Morris-Lecar neuron inhomogeneous distribution of ion channels ring network
ISSN号	1000-3290
DOI	10.7498/aps.62.240507
英文摘要	In this paper, we investigate the evolution and transition of collective electric activities of neurons in a ring network, induced by inhomogeneous distribution of ion channels. The local kinetics is measured by Morris-Lecar under voltage coupling type. In the numerical studies, the effect of inhomogeneous distribution of ion channels is simulated by changing the conductance in ion channels embedded in the membrane, and the potential mechanism is discussed. The effect of diversity of conductance between calcium and potassium ions on the activating of the adjacent neurons, and the dependence of developed travelling wave on the coupling intensity, are investigated in detail. The activating and waking up the nonexcitable or quiescent neurons with type I and type II excitability, are investigated, respectively. The numerical results confirm that the adjacent neurons are activated and the stable travelling wave is developed in the ring network of neurons when the conductance of calcium ions is increased beyond a certain threshold or the conductance of potassium ions is reduced below another threshold; while the propagation of the travelling wave could be slowed down or suppressed when the conductance of calcium ions is reduced or the conductance of potassium ion is increased. The development or emergence of travelling wave and propagation are greatly dependent on the increase of conductance of calcium ions and the decrease of potassium conductance.
资助项目	National Natural Science Foundation of China[11265008]
WOS研究方向	Physics
语种	中文
出版者	CHINESE PHYSICAL SOC
WOS记录号	WOS:000329040100008
状态	已发表
内容类型	期刊论文
源URL	[http://119.78.100.223/handle/2XXMBERH/34563]
专题	理学院
通讯作者	Ma Jun
作者单位	Lanzhou Univ Technol, Dept Phys, Lanzhou 730050, Peoples R China
推荐引用方式 GB/T 7714	Wu Xin-Yi,Ma Jun,Xie Zhen-Bo. Effect of inhomogeneous distribution of ion channels on collective electric activities of neurons in a ring network[J]. ACTA PHYSICA SINICA,2013,62(24):240507.
APA	Wu Xin-Yi,Ma Jun,&Xie Zhen-Bo.(2013).Effect of inhomogeneous distribution of ion channels on collective electric activities of neurons in a ring network.ACTA PHYSICA SINICA,62(24),240507.
MLA	Wu Xin-Yi,et al."Effect of inhomogeneous distribution of ion channels on collective electric activities of neurons in a ring network".ACTA PHYSICA SINICA 62.24(2013):240507.