Synthesis of Reversible Fluorescence Quenched Probe for Cu2+ and Imaging in PK-15 cells | |
Zhang Yingpeng1; You Caixia1; Yang Yunshang1; Liu Xiaoyu1; Guo Huichen2; Dong Yuying1 | |
刊名 | CHINESE JOURNAL OF ORGANIC CHEMISTRY |
2016-06-25 | |
卷号 | 36期号:6页码:1401-1406 |
关键词 | pyrazoline fluorescent probe copper ions recognition PK-15 living cells |
ISSN号 | 0253-2786 |
DOI | 10.6023/cjoc201512033 |
英文摘要 | A new pyrazoline derivatre 1-(2-hydroxyphenyl)-4-(9-anthryl)-3-benzothiazole pyrazolin (P1) was designed and synthesized. The recognition properties of the target compound P1 with metal ions had been investigated by UV absorption and fluorescence spectrophotometry. The probe exhibits several favorable features, including instantaneous, reversible recognition, high sensitivity and selectivity to copper ions. Cytotoxicity test and fluorescent immunoassay results show that compound P1 has good biocompatibility and low toxicity with its IC50 value of 376.558 mu mol/L. |
资助项目 | Natural Science Foundation of Gansu Province[2014GS03265] |
WOS研究方向 | Chemistry |
语种 | 中文 |
出版者 | SCIENCE PRESS |
WOS记录号 | WOS:000384603800024 |
状态 | 已发表 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.223/handle/2XXMBERH/33664] |
专题 | 石油化工学院 |
通讯作者 | Zhang Yingpeng; Yang Yunshang |
作者单位 | 1.Lanzhou Univ Technol, Sch Petrochem Engn, Lanzhou 730050, Peoples R China 2.Chinese Acad Agr Sci, Lanzhou Vet Res Inst, Lanzhou 730050, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang Yingpeng,You Caixia,Yang Yunshang,et al. Synthesis of Reversible Fluorescence Quenched Probe for Cu2+ and Imaging in PK-15 cells[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2016,36(6):1401-1406. |
APA | Zhang Yingpeng,You Caixia,Yang Yunshang,Liu Xiaoyu,Guo Huichen,&Dong Yuying.(2016).Synthesis of Reversible Fluorescence Quenched Probe for Cu2+ and Imaging in PK-15 cells.CHINESE JOURNAL OF ORGANIC CHEMISTRY,36(6),1401-1406. |
MLA | Zhang Yingpeng,et al."Synthesis of Reversible Fluorescence Quenched Probe for Cu2+ and Imaging in PK-15 cells".CHINESE JOURNAL OF ORGANIC CHEMISTRY 36.6(2016):1401-1406. |
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