Heterogeneous synthesis of nitrogen-doped carbon dots prepared via anhydrous citric acid and melamine for selective and sensitive turn on-off-on detection of Hg (II), glutathione and its cellular imaging

doi:10.1016/j.snb.2017.08.130

CORC > 兰州理工大学 > 兰州理工大学 > 石油化工学院

	Heterogeneous synthesis of nitrogen-doped carbon dots prepared via anhydrous citric acid and melamine for selective and sensitive turn on-off-on detection of Hg (II), glutathione and its cellular imaging
	lqbal, Anam 1,2,3,4,5; lqbal, Kanwal 1,2,4,5; Xu, Lige 1,2,4,5; Li, Bo 1,2,4,5,6; Gong, Deyan 1,2,4,5; Liu, Xiaoyu 1,2,4,5,7; Guo, Yali 1,2,4,5; Liu, Weisheng 1,2,4,5; Qin, Wenwu 1,2,4,5; Guo, Huichen 3,4,5
刊名	SENSORS AND ACTUATORS B-CHEMICAL
	2018-02
卷号	255 页码:1130-1138
关键词	N-CDs On-off-on Sensor Hg (II) Glutathione Fluorescence cell imaging
ISSN号	0925-4005
DOI	10.1016/j.snb.2017.08.130
英文摘要	Herein a new kind of convenient, low-cost, environmentally friendly and high-output heterogeneous one step synthesis of nitrogen-doped carbon dots (N-CDs) was developed by reacting anhydrous citric acid used as the carbon source and melamine as the surface passivation for nitrogen source without the use of any acid, alkali, organic solvents or metal ions along with high quantum yield (40% +/- 0.06) by solid state method. The emission spectrum shows a strong peak at 440 nm when excited at 360 nm, in the detection only the Hg (II) can readily quench the Photoluminescence (PL) of the N-CDs due to the strong electrostatic interaction and electron transfer between N-CDs and Hg (II), upon the addition of GSH PL of the N-CDs can be recovered owing to the preferred combination of Hg (II) and GSH by forming the Hg (II)-S or Hg (II)-NH bond indicating a remarkably high selectivity towards Hg2+ and biothiols (especially for GSH) among other metals and amino acids with a detection limit as low as 20 nM and 40 nM. With no apparent cytotoxicity, N-CDs could enter the baby hamster kidney (BHK) cells, indicating a practical potential probe for cellular imaging and labeling. Endowed the resulting N-CDs possess excitation dependent PL properties with relatively high sensitivity and selectivity, for the detection of Hg (II) and GSH in aqueous media, environmental and biological sensing applications. (C) 2017 Elsevier B.V. All rights reserved.
资助项目	Gansu Province Natural Science Foundation of China[1508RJZA078]
WOS研究方向	Chemistry ; Electrochemistry ; Instruments & Instrumentation
语种	英语
出版者	ELSEVIER SCIENCE SA
WOS记录号	WOS:000414151800133
状态	已发表
内容类型	期刊论文
源URL	[http://119.78.100.223/handle/2XXMBERH/32821]
专题	石油化工学院
通讯作者	Qin, Wenwu; Guo, Huichen
作者单位	1.Lanzhou Univ, Coll Chem & Chem Engn, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Peoples R China 2.Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 3.Univ Balochistan, Quetta, Pakistan 4.Chinese Acad Agr Sci, Lanzhou Vet Res Inst, State Key Lab Vet Etiol Biol, Xujiaping 1, Lanzhou 730046, Gansu, Peoples R China 5.Chinese Acad Agr Sci, Lanzhou Vet Res Inst, Key Lab Anim Virol, Minist Agr, Xujiaping 1, Lanzhou 730046, Gansu, Peoples R China 6.Chinese Acad Sci, Qinghai Inst Salt Lakes, Xining 810008, Qinghai, Peoples R China 7.Lanzhou Univ Technol, Coll Petrochem Technol, Lanzhou 730050, Gansu, Peoples R China
推荐引用方式 GB/T 7714	lqbal, Anam,lqbal, Kanwal,Xu, Lige,et al. Heterogeneous synthesis of nitrogen-doped carbon dots prepared via anhydrous citric acid and melamine for selective and sensitive turn on-off-on detection of Hg (II), glutathione and its cellular imaging[J]. SENSORS AND ACTUATORS B-CHEMICAL,2018,255:1130-1138.
APA	lqbal, Anam.,lqbal, Kanwal.,Xu, Lige.,Li, Bo.,Gong, Deyan.,...&Guo, Huichen.(2018).Heterogeneous synthesis of nitrogen-doped carbon dots prepared via anhydrous citric acid and melamine for selective and sensitive turn on-off-on detection of Hg (II), glutathione and its cellular imaging.SENSORS AND ACTUATORS B-CHEMICAL,255,1130-1138.
MLA	lqbal, Anam,et al."Heterogeneous synthesis of nitrogen-doped carbon dots prepared via anhydrous citric acid and melamine for selective and sensitive turn on-off-on detection of Hg (II), glutathione and its cellular imaging".SENSORS AND ACTUATORS B-CHEMICAL 255(2018):1130-1138.